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Oral chloral hydrate — Competitive Intelligence Brief
marketed
Sedative-hypnotic
GABA-A receptor
Neurology / Sleep Medicine
Small molecule
Live · refreshed every 30 min
Target snapshot
Oral chloral hydrate (Oral chloral hydrate) — Seoul National University Hospital. Chloral hydrate is a sedative-hypnotic that enhances inhibitory neurotransmission in the central nervous system, primarily through potentiation of GABA receptors.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Oral chloral hydrate TARGET | Oral chloral hydrate | Seoul National University Hospital | marketed | Sedative-hypnotic | GABA-A receptor | |
| Zulresso | BREXANOLONE | Sage Therap | marketed | Neuroactive Steroid Gamma-Aminobutyric Acid A Receptor Positive Modulator | GABA-A receptor alpha-1/beta-2/gamma-2 | 2019-01-01 |
| Onfi | CLOBAZAM | Lundbeck Pharms Llc | marketed | Benzodiazepine [EPC] | GABA-A receptor alpha-1/beta-2/gamma-2 | 2011-01-01 |
| Lusedra | FOSPROPOFOL | marketed | fospropofol | GABA-A receptor | 2008-01-01 | |
| Campral | ACAMPROSATE | Allergan/AbbVie | marketed | acamprosate | GABA-A receptor alpha-1/beta-3/gamma-2 | 2004-01-01 |
| Sonata | ZALEPLON | Pfizer | marketed | gamma-Aminobutyric Acid A Receptor Agonist [EPC] | GABA-A receptor alpha-1/beta-2/gamma-2 | 1999-01-01 |
| Suprane | DESFLURANE | Baxter | marketed | General Anesthetic [EPC] | GABA-A receptor; anion channel | 1992-01-01 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
- — Onfi · 12403090 · Formulation · US
- — Onfi · 12290597 · Formulation · US
- — Onfi · 11541002 · Formulation · US
Sponsor landscape (Sedative-hypnotic class)
- Hospira, now a wholly owned subsidiary of Pfizer · 1 drug in this class
- Life Extension Foundation Inc. · 1 drug in this class
- Seoul National University Hospital · 1 drug in this class
- University Hospital, Brest · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Oral chloral hydrate — Competitive Intelligence Brief. https://druglandscape.com/ci/oral-chloral-hydrate. Accessed 2026-05-16.
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