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Open label fondaparinux — Competitive Intelligence Brief

Open label fondaparinux (Open label fondaparinux) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Factor Xa inhibitor. Area: Cardiovascular.

marketed Factor Xa inhibitor Factor Xa Cardiovascular Small molecule Live · refreshed every 30 min

Target snapshot

Open label fondaparinux (Open label fondaparinux) — GlaxoSmithKline. Fondaparinux selectively inhibits Factor Xa, a key enzyme in the coagulation cascade, thereby preventing thrombin generation and blood clot formation.

Comparator set (6 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Open label fondaparinux TARGET Open label fondaparinux GlaxoSmithKline marketed Factor Xa inhibitor Factor Xa
Hympavzi MARSTACIMAB Pfizer Inc marketed Monoclonal Antibody Factor Xa 2025-01-01
Eliquis apixaban Bristol-Myers Squibb marketed Factor Xa inhibitor Factor Xa (FXa) 2012-01-01
Xarelto rivaroxaban Johnson & Johnson marketed Direct Factor Xa Inhibitor Factor Xa (FXa) 2011-01-01
Heparin Sodium In Plastic Container Heparin Sodium Fresenius Kabi marketed Anti-coagulant Antithrombin III, Factor Xa, Factor IIa 1939-01-01
Usual dose adjustment of enoxaparin Usual dose adjustment of enoxaparin Assistance Publique - Hôpitaux de Paris marketed Low-molecular-weight heparin (LMWH) Factor Xa and Factor IIa (via antithrombin III)
Nebulized heparin and salbutamol Nebulized heparin and salbutamol Ain Shams University marketed Combination therapy: anticoagulant + bronchodilator Heparin: Factor IIa and Factor Xa; Salbutamol: Beta-2 adrenergic receptor

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

Sponsor landscape (Factor Xa inhibitor class)

  1. GlaxoSmithKline · 4 drugs in this class
  2. Bayer · 2 drugs in this class
  3. China National Center for Cardiovascular Diseases · 1 drug in this class
  4. Hoffmann-La Roche · 1 drug in this class
  5. Kim, Seok Jin · 1 drug in this class
  6. NYU Langone Health · 1 drug in this class
  7. Paul Di Cesare,MD · 1 drug in this class
  8. Pfizer · 1 drug in this class
  9. Queen Mary University of London · 1 drug in this class
  10. Queen's University · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Open label fondaparinux — Competitive Intelligence Brief. https://druglandscape.com/ci/open-label-fondaparinux. Accessed 2026-05-16.

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