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OPC-61815 injection — Competitive Intelligence Brief

OPC-61815 injection (OPC-61815 injection) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: NK1 receptor antagonist. Area: Oncology / Supportive Care.

phase 3 NK1 receptor antagonist NK1 receptor (neurokinin-1 receptor) Oncology / Supportive Care Small molecule Live · refreshed every 30 min

Target snapshot

OPC-61815 injection (OPC-61815 injection) — Otsuka Pharmaceutical Co., Ltd.. OPC-61815 is a selective antagonist of the neurokinin-1 (NK1) receptor that reduces substance P signaling in the central nervous system.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
OPC-61815 injection TARGET OPC-61815 injection Otsuka Pharmaceutical Co., Ltd. phase 3 NK1 receptor antagonist NK1 receptor (neurokinin-1 receptor)
fosnetupitant/ palonosetron fosnetupitant/ palonosetron Helsinn Healthcare SA marketed NK1 receptor antagonist / 5-HT3 receptor antagonist combination NK1 receptor (substance P receptor) / 5-HT3 receptor
Aprepitant plus Ondansetron Aprepitant plus Ondansetron University of Pittsburgh marketed NK1 receptor antagonist + 5-HT3 receptor antagonist combination NK1 receptor (aprepitant); 5-HT3 receptor (ondansetron)
Fosaprepitant for Injection Fosaprepitant for Injection Montefiore Medical Center marketed NK1 receptor antagonist NK1 receptor (neurokinin-1 receptor)
Akynzeo solution Akynzeo solution Helsinn Healthcare SA marketed NK1 receptor antagonist / 5-HT3 receptor antagonist combination NK1 receptor (netupitant component); 5-HT3 receptor (palonosetron component)
MK0733 / Duration of Treatment: 18 Weeks MK0733 / Duration of Treatment: 18 Weeks Organon and Co phase 3 NK1 receptor antagonist NK1 receptor (neurokinin-1 receptor)
Standard: Aprepitant Standard: Aprepitant CCTU phase 3 NK1 receptor antagonist NK1 receptor

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (NK1 receptor antagonist class)

  1. Merck Sharp & Dohme LLC · 4 drugs in this class
  2. GlaxoSmithKline · 3 drugs in this class
  3. Organon and Co · 3 drugs in this class
  4. CCTU · 2 drugs in this class
  5. Acacia Pharma Ltd · 2 drugs in this class
  6. Sanofi · 1 drug in this class
  7. Santen SAS · 1 drug in this class
  8. CR-CSSS Champlain-Charles-Le Moyne · 1 drug in this class
  9. Montefiore Medical Center · 1 drug in this class
  10. New Mexico Cancer Research Alliance · 1 drug in this class

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Cite this brief

Drug Landscape (2026). OPC-61815 injection — Competitive Intelligence Brief. https://druglandscape.com/ci/opc-61815-injection. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing