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Ondansetron Intraperitoneal Lavage — Competitive Intelligence Brief

Ondansetron Intraperitoneal Lavage (Ondansetron Intraperitoneal Lavage) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: 5-HT3 receptor antagonist. Area: Gastroenterology / Oncology.

marketed 5-HT3 receptor antagonist 5-HT3 receptor Gastroenterology / Oncology Small molecule Live · refreshed every 30 min

Target snapshot

Ondansetron Intraperitoneal Lavage (Ondansetron Intraperitoneal Lavage) — Instituto Mexicano del Seguro Social. Ondansetron blocks serotonin 5-HT3 receptors in the peritoneal cavity to prevent nausea and vomiting during intraperitoneal lavage procedures.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Ondansetron Intraperitoneal Lavage TARGET Ondansetron Intraperitoneal Lavage Instituto Mexicano del Seguro Social marketed 5-HT3 receptor antagonist 5-HT3 receptor
Trintellix vortioxetine Takeda marketed Serotonin modulator and stimulator (SMS); SSRI-like agent Serotonin transporter (SERT); 5-HT3 receptor; 5-HT1A receptor 2013-01-01
Dexamethasone, Ondansetron, Aprepitant Dexamethasone, Ondansetron, Aprepitant Ottawa Hospital Research Institute marketed Antiemetic combination (corticosteroid + 5-HT3 antagonist + NK1 antagonist) Glucocorticoid receptor, 5-HT3 receptor, NK1 receptor
Sodium Bicarbonate Powder and ondansetron Sodium Bicarbonate Powder and ondansetron Aya Sabry Mohamed Mohamed marketed Antacid and antiemetic combination 5-HT3 receptor (ondansetron); non-specific acid neutralization (sodium bicarbonate)
ramosetron, ondansetron, dexamethasone ramosetron, ondansetron, dexamethasone Government Medical College, Haldwani marketed 5-HT3 receptor antagonist + corticosteroid combination 5-HT3 receptor (ramosetron, ondansetron); glucocorticoid receptor (dexamethasone)
Akynzeo solution Akynzeo solution Helsinn Healthcare SA marketed NK1 receptor antagonist / 5-HT3 receptor antagonist combination NK1 receptor (netupitant component); 5-HT3 receptor (palonosetron component)
cardiac output changes with "ondansetron" cardiac output changes with "ondansetron" University Tunis El Manar marketed 5-HT3 receptor antagonist 5-HT3 receptor

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (5-HT3 receptor antagonist class)

  1. Helsinn Healthcare SA · 4 drugs in this class
  2. LG Life Sciences · 3 drugs in this class
  3. University of Malaya · 2 drugs in this class
  4. GlaxoSmithKline · 1 drug in this class
  5. Hamad Medical Corporation · 1 drug in this class
  6. Eye & ENT Hospital of Fudan University · 1 drug in this class
  7. Instituto Mexicano del Seguro Social · 1 drug in this class
  8. Chongqing University Cancer Hospital · 1 drug in this class
  9. Merck Sharp & Dohme LLC · 1 drug in this class
  10. MonoSol Rx · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Ondansetron Intraperitoneal Lavage — Competitive Intelligence Brief. https://druglandscape.com/ci/ondansetron-intraperitoneal-lavage. Accessed 2026-05-17.

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