Who are Zofran's main competitors?

No direct comparators detected in our index.

How often does this brief refresh?

Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-06-10 · How we verify

Zofran — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Zofran (ondansetron) competitive landscape: 0 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: 5-HT3 receptor antagonist (antiemetic). Area: Gastroenterology.

marketed 5-HT3 receptor antagonist (antiemetic) Aldehyde oxidase, 5-hydroxytryptamine receptor 3B, Multidrug and toxin extrusion protein 1 Gastroenterology Small molecule Live · refreshed every 30 min

Target snapshot

Zofran (ondansetron) — GSK (originally Glaxo). Selective 5-HT3 receptor antagonist that blocks serotonin-mediated nausea and vomiting signals in the CTZ and vagal afferents.

Comparator set

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Zofran TARGET	ondansetron	GSK (originally Glaxo)	marketed	5-HT3 receptor antagonist (antiemetic)	Aldehyde oxidase, 5-hydroxytryptamine receptor 3B, Multidrug and toxin extrusion protein 1	1991-01-04

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

2029-11-23 — Zofran · 8580830 · Formulation · US
2030-07-13 — Zofran · 9095577 · Formulation · US

Sponsor landscape (5-HT3 receptor antagonist (antiemetic) class)

GSK (originally Glaxo) · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Zofran — Competitive Intelligence Brief. https://druglandscape.com/ci/ondansetron. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing