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olmesartan, hydrochlorothiazide, amlodipine — Competitive Intelligence Brief
marketed
Antihypertensive combination (ARB + thiazide diuretic + calcium channel blocker)
Angiotensin II type 1 receptor (AT1R), sodium-chloride cotransporter (NCC), L-type calcium channel
Cardiovascular
Small molecule
Live · refreshed every 30 min
Target snapshot
olmesartan, hydrochlorothiazide, amlodipine (olmesartan, hydrochlorothiazide, amlodipine) — The Louis & Rachel Rudin Foundation. This triple-combination antihypertensive reduces blood pressure through three complementary mechanisms: blocking angiotensin II receptors, inhibiting sodium reabsorption in the kidney, and relaxing vascular smooth muscle.
Comparator set (1 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| olmesartan, hydrochlorothiazide, amlodipine TARGET | olmesartan, hydrochlorothiazide, amlodipine | The Louis & Rachel Rudin Foundation | marketed | Antihypertensive combination (ARB + thiazide diuretic + calcium channel blocker) | Angiotensin II type 1 receptor (AT1R), sodium-chloride cotransporter (NCC), L-type calcium channel | |
| candesartan cilexetil + chlorthalidone + amlodipine | candesartan cilexetil + chlorthalidone + amlodipine | Hospital Israelita Albert Einstein | phase 3 | Antihypertensive combination (ARB + thiazide diuretic + calcium channel blocker) | Angiotensin II type 1 receptor (AT1R), sodium-chloride cotransporter (NCC), L-type calcium channel |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Antihypertensive combination (ARB + thiazide diuretic + calcium channel blocker) class)
- Hospital Israelita Albert Einstein · 1 drug in this class
- The Louis & Rachel Rudin Foundation · 1 drug in this class
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Cite this brief
Drug Landscape (2026). olmesartan, hydrochlorothiazide, amlodipine — Competitive Intelligence Brief. https://druglandscape.com/ci/olmesartan-hydrochlorothiazide-amlodipine. Accessed 2026-05-17.
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