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olanzapine + fluoxetine — Competitive Intelligence Brief
marketed
Atypical antipsychotic + SSRI combination
Dopamine D2 receptor, serotonin 5-HT2A receptor, serotonin transporter (SERT)
Psychiatry
Small molecule
Live · refreshed every 30 min
Target snapshot
olanzapine + fluoxetine (olanzapine + fluoxetine) — University of Florida. Olanzapine blocks dopamine and serotonin receptors while fluoxetine inhibits serotonin reuptake, together providing antipsychotic and antidepressant effects.
Comparator set (1 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| olanzapine + fluoxetine TARGET | olanzapine + fluoxetine | University of Florida | marketed | Atypical antipsychotic + SSRI combination | Dopamine D2 receptor, serotonin 5-HT2A receptor, serotonin transporter (SERT) | |
| Olanzapine-Fluoxetine Combination | Olanzapine-Fluoxetine Combination | All India Institute of Medical Sciences, Bhubaneswar | marketed | Atypical antipsychotic + SSRI combination | Dopamine D2 receptor, serotonin 5-HT2A receptor, serotonin transporter (SERT) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Atypical antipsychotic + SSRI combination class)
- All India Institute of Medical Sciences, Bhubaneswar · 1 drug in this class
- University of Florida · 1 drug in this class
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Cite this brief
Drug Landscape (2026). olanzapine + fluoxetine — Competitive Intelligence Brief. https://druglandscape.com/ci/olanzapine-fluoxetine. Accessed 2026-05-16.
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