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Ofatumumab combined with daratumumab — Competitive Intelligence Brief
phase 3
Monoclonal antibody combination
CD20 (ofatumumab) and CD38 (daratumumab)
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
Ofatumumab combined with daratumumab (Ofatumumab combined with daratumumab) — The First People's Hospital of Changzhou. Ofatumumab and daratumumab are monoclonal antibodies that work synergistically to target and eliminate malignant B cells and plasma cells by binding to CD20 and CD38 respectively, triggering immune-mediated cell death.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Ofatumumab combined with daratumumab TARGET | Ofatumumab combined with daratumumab | The First People's Hospital of Changzhou | phase 3 | Monoclonal antibody combination | CD20 (ofatumumab) and CD38 (daratumumab) | |
| daclizumab, infliximab | daclizumab, infliximab | University of Iowa | marketed | Monoclonal antibody combination | IL-2 receptor alpha (CD25) and TNF-alpha | |
| Casirivimab and Imdevimab Drug Combination | Casirivimab and Imdevimab Drug Combination | Mansoura University Hospital | marketed | Monoclonal antibody combination (SARS-CoV-2 neutralizing antibodies) | SARS-CoV-2 spike protein receptor-binding domain | |
| Lilly Bamlanivimab + Etesevimab | Lilly Bamlanivimab + Etesevimab | Erin McCreary | marketed | Monoclonal antibody combination (neutralizing antibodies) | SARS-CoV-2 spike protein receptor-binding domain | |
| Trastuzumab + Pertuzumab | Trastuzumab + Pertuzumab | Massachusetts General Hospital | marketed | HER2-targeted monoclonal antibody combination | HER2 (human epidermal growth factor receptor 2) | |
| Pertuzumab + trastuzumab | Pertuzumab + trastuzumab | European Organisation for Research and Treatment of Cancer - EORTC | marketed | HER2-targeted monoclonal antibody combination | HER2 (human epidermal growth factor receptor 2) | |
| Regeneron Casirivimab + Imdevimab | Regeneron Casirivimab + Imdevimab | Erin McCreary | marketed | Monoclonal antibody combination (neutralizing antibodies) | SARS-CoV-2 spike protein |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Monoclonal antibody combination class)
- AstraZeneca · 1 drug in this class
- National Institute of Allergy and Infectious Diseases (NIAID) · 1 drug in this class
- The First People's Hospital of Changzhou · 1 drug in this class
- University of Iowa · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Ofatumumab combined with daratumumab — Competitive Intelligence Brief. https://druglandscape.com/ci/ofatumumab-combined-with-daratumumab. Accessed 2026-05-16.
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