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Ofatumumab combined with daratumumab — Competitive Intelligence Brief

Ofatumumab combined with daratumumab (Ofatumumab combined with daratumumab) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Monoclonal antibody combination. Area: Oncology.

phase 3 Monoclonal antibody combination CD20 (ofatumumab) and CD38 (daratumumab) Oncology Small molecule Live · refreshed every 30 min

Target snapshot

Ofatumumab combined with daratumumab (Ofatumumab combined with daratumumab) — The First People's Hospital of Changzhou. Ofatumumab and daratumumab are monoclonal antibodies that work synergistically to target and eliminate malignant B cells and plasma cells by binding to CD20 and CD38 respectively, triggering immune-mediated cell death.

Comparator set (6 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Ofatumumab combined with daratumumab TARGET Ofatumumab combined with daratumumab The First People's Hospital of Changzhou phase 3 Monoclonal antibody combination CD20 (ofatumumab) and CD38 (daratumumab)
daclizumab, infliximab daclizumab, infliximab University of Iowa marketed Monoclonal antibody combination IL-2 receptor alpha (CD25) and TNF-alpha
Casirivimab and Imdevimab Drug Combination Casirivimab and Imdevimab Drug Combination Mansoura University Hospital marketed Monoclonal antibody combination (SARS-CoV-2 neutralizing antibodies) SARS-CoV-2 spike protein receptor-binding domain
Lilly Bamlanivimab + Etesevimab Lilly Bamlanivimab + Etesevimab Erin McCreary marketed Monoclonal antibody combination (neutralizing antibodies) SARS-CoV-2 spike protein receptor-binding domain
Trastuzumab + Pertuzumab Trastuzumab + Pertuzumab Massachusetts General Hospital marketed HER2-targeted monoclonal antibody combination HER2 (human epidermal growth factor receptor 2)
Pertuzumab + trastuzumab Pertuzumab + trastuzumab European Organisation for Research and Treatment of Cancer - EORTC marketed HER2-targeted monoclonal antibody combination HER2 (human epidermal growth factor receptor 2)
Regeneron Casirivimab + Imdevimab Regeneron Casirivimab + Imdevimab Erin McCreary marketed Monoclonal antibody combination (neutralizing antibodies) SARS-CoV-2 spike protein

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Monoclonal antibody combination class)

  1. AstraZeneca · 1 drug in this class
  2. National Institute of Allergy and Infectious Diseases (NIAID) · 1 drug in this class
  3. The First People's Hospital of Changzhou · 1 drug in this class
  4. University of Iowa · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Ofatumumab combined with daratumumab — Competitive Intelligence Brief. https://druglandscape.com/ci/ofatumumab-combined-with-daratumumab. Accessed 2026-05-16.

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