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O6-benzylguanine — Competitive Intelligence Brief

O6-benzylguanine (O6-benzylguanine) competitive landscape: 0 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: DNA repair inhibitor / Alkyltransferase inhibitor. Area: Oncology.

phase 3 DNA repair inhibitor / Alkyltransferase inhibitor O6-alkylguanine-DNA alkyltransferase (AGT) Oncology Small molecule Live · refreshed every 30 min

Target snapshot

O6-benzylguanine (O6-benzylguanine) — Case Comprehensive Cancer Center. O6-benzylguanine is an alkyltransferase inhibitor that depletes the DNA repair protein O6-alkylguanine-DNA alkyltransferase (AGT), sensitizing cancer cells to alkylating chemotherapy agents.

Comparator set

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
O6-benzylguanine TARGET O6-benzylguanine Case Comprehensive Cancer Center phase 3 DNA repair inhibitor / Alkyltransferase inhibitor O6-alkylguanine-DNA alkyltransferase (AGT)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (DNA repair inhibitor / Alkyltransferase inhibitor class)

  1. Case Comprehensive Cancer Center · 1 drug in this class

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Cite this brief

Drug Landscape (2026). O6-benzylguanine — Competitive Intelligence Brief. https://druglandscape.com/ci/o6-benzylguanine. Accessed 2026-05-17.

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