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Nystatin oral suspension — Competitive Intelligence Brief
marketed
Polyene macrolide antifungal
Ergosterol
Infectious Disease
Small molecule
Live · refreshed every 30 min
Target snapshot
Nystatin oral suspension (Nystatin oral suspension) — Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections. Nystatin binds to ergosterol in fungal cell membranes, creating pores that cause leakage and cell death.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Nystatin oral suspension TARGET | Nystatin oral suspension | Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections | marketed | Polyene macrolide antifungal | Ergosterol | |
| Mycostatin | nystatin | Generic (originally Squibb) | marketed | Polyene Antifungal [EPC] | Ergosterol (fungal cell membrane) | 1954-01-01 |
| Liposomal Amphotericin B | Liposomal Amphotericin B | Taiwan Liposome Company | marketed | Polyene antifungal | Ergosterol | |
| Nystatin 10000U/ml | Nystatin 10000U/ml | Riyadh Colleges of Dentistry and Pharmacy | marketed | Polyene macrolide antifungal | Ergosterol | |
| Amphotericin B Deoxycholate | Amphotericin B Deoxycholate | Drugs for Neglected Diseases | marketed | Polyene antifungal | Ergosterol | |
| Loceryl NL + Cosmetic varnish | Loceryl NL + Cosmetic varnish | Galderma R&D | marketed | Morpholine antifungal | Δ14-steroid reductase and Δ8→Δ7-isomerase (ergosterol biosynthesis pathway) | |
| liposomal amphotericin B + paromomycin | liposomal amphotericin B + paromomycin | Drugs for Neglected Diseases | phase 3 | Antifungal/antiparasitic combination | Ergosterol (amphotericin B); ribosomal protein synthesis (paromomycin) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Polyene macrolide antifungal class)
- Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections · 1 drug in this class
- Riyadh Colleges of Dentistry and Pharmacy · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Nystatin oral suspension — Competitive Intelligence Brief. https://druglandscape.com/ci/nystatin-oral-suspension. Accessed 2026-05-17.
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