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NVP and AZT — Competitive Intelligence Brief
phase 3
Antiretroviral combination therapy (NNRTI + NRTI)
HIV reverse transcriptase
Infectious Disease / Virology
Small molecule
Live · refreshed every 30 min
Target snapshot
NVP and AZT (NVP and AZT) — Johns Hopkins Bloomberg School of Public Health. NVP and AZT are nucleoside reverse transcriptase inhibitors (NRTIs) that block HIV reverse transcriptase to prevent viral replication.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| NVP and AZT TARGET | NVP and AZT | Johns Hopkins Bloomberg School of Public Health | phase 3 | Antiretroviral combination therapy (NNRTI + NRTI) | HIV reverse transcriptase | |
| didanosine + lamivudine + efavirenz | didanosine + lamivudine + efavirenz | Clinical Trial Agency of HIV Study Group | marketed | Antiretroviral combination therapy (NRTI + NNRTI) | HIV reverse transcriptase | |
| DTG/3TC/ABC + ELV/COBI/FTC/TAF | DTG/3TC/ABC + ELV/COBI/FTC/TAF | Fundacion SEIMC-GESIDA | marketed | Antiretroviral combination therapy (integrase inhibitor + nucleoside/nucleotide reverse transcriptase inhibitors) | HIV integrase, HIV reverse transcriptase | |
| Combivir+Kaletra | Combivir+Kaletra | Hospital Clinic of Barcelona | marketed | Antiretroviral combination therapy (NRTI + protease inhibitor) | HIV reverse transcriptase and HIV protease | |
| Didanosine (enteric-coated) | Didanosine (enteric-coated) | Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections | marketed | Nucleoside reverse transcriptase inhibitor (NRTI) | HIV reverse transcriptase | |
| ELV/COBI/FTC/TAF | ELV/COBI/FTC/TAF | Fundacion SEIMC-GESIDA | marketed | Antiretroviral combination therapy (integrase inhibitor + NRTI + NtRTI + pharmacokinetic booster) | HIV integrase, HIV reverse transcriptase | |
| Tenofovir/Emtricitabine | Tenofovir/Emtricitabine | Bristol-Myers Squibb | marketed | Nucleoside/nucleotide reverse transcriptase inhibitor (NRTI/NtRTI) combination | HIV reverse transcriptase |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Antiretroviral combination therapy (NNRTI + NRTI) class)
- Johns Hopkins Bloomberg School of Public Health · 2 drugs in this class
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Cite this brief
Drug Landscape (2026). NVP and AZT — Competitive Intelligence Brief. https://druglandscape.com/ci/nvp-and-azt. Accessed 2026-05-17.
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