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NTX/PBO-B — Competitive Intelligence Brief
phase 3
Combination antiobesity agent (opioid antagonist + antidepressant)
Opioid receptors (naltrexone); norepinephrine and dopamine transporters (bupropion)
Obesity / Metabolic Disease
Small molecule
Live · refreshed every 30 min
Target snapshot
NTX/PBO-B (NTX/PBO-B) — Alkermes, Inc.. NTX/PBO-B is a combination of naltrexone (an opioid antagonist) and bupropion (an antidepressant) designed to reduce appetite and promote weight loss.
Comparator set
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| NTX/PBO-B TARGET | NTX/PBO-B | Alkermes, Inc. | phase 3 | Combination antiobesity agent (opioid antagonist + antidepressant) | Opioid receptors (naltrexone); norepinephrine and dopamine transporters (bupropion) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Combination antiobesity agent (opioid antagonist + antidepressant) class)
- Alkermes, Inc. · 1 drug in this class
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Cite this brief
Drug Landscape (2026). NTX/PBO-B — Competitive Intelligence Brief. https://druglandscape.com/ci/ntx-pbo-b. Accessed 2026-06-10.
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