Last reviewed · How we verify
non-immunogenic staphylokinase — Competitive Intelligence Brief
phase 3
Fibrinolytic agent
Plasminogen
Cardiovascular
Small molecule
Live · refreshed every 30 min
Target snapshot
non-immunogenic staphylokinase (non-immunogenic staphylokinase) — Supergene, LLC. Non-immunogenic staphylokinase is a genetically engineered enzyme that catalyzes the conversion of plasminogen to plasmin, thereby dissolving blood clots.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| non-immunogenic staphylokinase TARGET | non-immunogenic staphylokinase | Supergene, LLC | phase 3 | Fibrinolytic agent | Plasminogen | |
| Activase | ALTEPLASE | Roche | marketed | Plasminogen | 1996-01-01 | |
| Trasylol | APROTININ | Bayer | marketed | Antifibrinolytic Agent | Plasminogen | 1993-01-01 |
| Cyklokapron | TRANEXAMIC ACID | Exela Pharma | marketed | Antifibrinolytic Agent [EPC] | Plasminogen | 1986-01-01 |
| Amicar | AMINOCAPROIC ACID | Epic Pharma Llc | marketed | Antifibrinolytic Agent [EPC] | Plasminogen | 1964-01-01 |
| UPA-ECx2 | UPA-ECx2 | Oregon Health and Science University | marketed | uPA (urokinase plasminogen activator) | ||
| Silymarin | Silymarin | F.D. Roosevelt Teaching Hospital with Policlinic Banska Bystrica | marketed | silymarin | Urokinase-type plasminogen activator, Carbonic anhydrase 1, Carbonic anhydrase 12 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Fibrinolytic agent class)
- Capital Medical University · 1 drug in this class
- Kedrion S.p.A. · 1 drug in this class
- Supergene, LLC · 1 drug in this class
- University of North Carolina, Chapel Hill · 1 drug in this class
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Cite this brief
Drug Landscape (2026). non-immunogenic staphylokinase — Competitive Intelligence Brief. https://druglandscape.com/ci/non-immunogenic-staphylokinase. Accessed 2026-05-16.
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