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NL003 — Competitive Intelligence Brief
phase 3
Cytokine / IL-2 receptor agonist
IL-2 receptor
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
NL003 (NL003) — Beijing Northland Biotech. Co., Ltd.. NL003 is a recombinant human IL-2 mutein that selectively activates IL-2 receptor signaling to enhance immune cell proliferation and anti-tumor activity.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| NL003 TARGET | NL003 | Beijing Northland Biotech. Co., Ltd. | phase 3 | Cytokine / IL-2 receptor agonist | IL-2 receptor | |
| vemurafenib + HD IL-2 | vemurafenib + HD IL-2 | Clinigen, Inc. | marketed | BRAF inhibitor + cytokine immunotherapy | BRAF V600E kinase; IL-2 receptor | |
| Basiliximab, Tacrolimus, MMF, Prednisolon | Basiliximab, Tacrolimus, MMF, Prednisolon | University Hospital Freiburg | marketed | Immunosuppressive combination regimen | IL-2 receptor (basiliximab), calcineurin (tacrolimus), IMPDH (MMF), glucocorticoid receptor (prednisolone) | |
| IL-2 (interleukin 2) | IL-2 (interleukin 2) | King's College London | marketed | Cytokine | IL-2 receptor (IL-2R) | |
| histamine dihydrochloride and IL-2 | histamine dihydrochloride and IL-2 | Cytovia, Inc. | marketed | Immunomodulator combination | Histamine receptors (H1, H2, H3, H4) and IL-2 receptor | |
| anti-CD25 rhMAb | anti-CD25 rhMAb | Peking University People's Hospital | marketed | CD25 antagonist monoclonal antibody | CD25 (IL-2 receptor alpha chain) | |
| Basiliximab treatment | Basiliximab treatment | Nantes University Hospital | marketed | Monoclonal antibody; IL-2 receptor antagonist | CD25 (IL-2 receptor alpha chain) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Cytokine / IL-2 receptor agonist class)
- Beijing Northland Biotech. Co., Ltd. · 1 drug in this class
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Cite this brief
Drug Landscape (2026). NL003 — Competitive Intelligence Brief. https://druglandscape.com/ci/nl003. Accessed 2026-05-14.
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