Who are Nivolumab or pembrolizumab's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Keytruda, Vevye®, Chemotherapy+Pembrolizumab., SOX plus PD-1 inhibitor, Nivolumab in combination with Ipilimumab, Actilitio®.

How often does this brief refresh?

Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

How do I get this as a recurring report?

Subscribe to /feed/ci/nivolumab-or-pembrolizumab.xml in any RSS reader (Feedly, Inoreader, NewsBlur). Every regulatory action, trial readout, or patent event lands in your feed automatically.

Last reviewed 2026-05-16 · How we verify

Nivolumab or pembrolizumab — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Nivolumab or pembrolizumab (Nivolumab or pembrolizumab) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: PD-1 inhibitor. Area: Oncology.

phase 3 PD-1 inhibitor PD-1 (Programmed Death-1) Oncology Small molecule Live · refreshed every 30 min

Target snapshot

Nivolumab or pembrolizumab (Nivolumab or pembrolizumab) — Asan Medical Center. These drugs block the PD-1 checkpoint protein on immune cells, allowing the immune system to recognize and attack cancer cells.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Nivolumab or pembrolizumab TARGET	Nivolumab or pembrolizumab	Asan Medical Center	phase 3	PD-1 inhibitor	PD-1 (Programmed Death-1)
Keytruda	pembrolizumab	Merck & Co.	marketed	Monoclonal antibody; PD-1 inhibitor	PD-1 receptor	2014-09-04
Vevye®	Vevye®	Baylor College of Medicine	marketed	PD-1 inhibitor	PD-1
Chemotherapy+Pembrolizumab.	Chemotherapy+Pembrolizumab.	Tang-Du Hospital	marketed	Chemotherapy + PD-1 inhibitor combination	PD-1 (programmed death receptor 1); chemotherapy targets DNA
SOX plus PD-1 inhibitor	SOX plus PD-1 inhibitor	Liaoning Cancer Hospital & Institute	marketed	Chemotherapy + PD-1 inhibitor combination	PD-1 (programmed death receptor 1); S-1 (thymidylate synthase/5-FU metabolism); oxaliplatin (DNA cross-linking)
Nivolumab in combination with Ipilimumab	Nivolumab in combination with Ipilimumab	Bristol-Myers Squibb	marketed	Checkpoint inhibitor combination (PD-1 inhibitor + CTLA-4 inhibitor)	PD-1 and CTLA-4
Actilitio®	Actilitio®	Centro de Atencion e Investigacion Medica	marketed	PD-1 inhibitor	PD-1

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (PD-1 inhibitor class)

Sun Yat-sen University · 11 drugs in this class
Bristol-Myers Squibb · 9 drugs in this class
Addpharma Inc. · 7 drugs in this class
Merck Sharp & Dohme LLC · 5 drugs in this class
Shanghai Henlius Biotech · 5 drugs in this class
Innovent Biologics (Suzhou) Co. Ltd. · 5 drugs in this class
Pfizer · 4 drugs in this class
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · 4 drugs in this class
Amgen · 3 drugs in this class
Daewoong Pharmaceutical Co. LTD. · 3 drugs in this class

Subscribe to ongoing alerts

Push every new event for this competitive set into your RSS reader, IFTTT/Zapier workflow, or email digest:

Cite this brief

Drug Landscape (2026). Nivolumab or pembrolizumab — Competitive Intelligence Brief. https://druglandscape.com/ci/nivolumab-or-pembrolizumab. Accessed 2026-05-16.

Build your own brief

Pick any drug + add comparators:

https://druglandscape.com/ci/{slug} — auto-detected competitors
https://druglandscape.com/ci/{slug}?vs=drug1,drug2,drug3 — explicit comparators
Brand names auto-resolve: /ci/keytruda → 301 → /ci/pembrolizumab