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Nicotine polacrilex, Bupropion — Competitive Intelligence Brief
phase 3
Nicotine replacement therapy combined with antidepressant
Nicotinic acetylcholine receptors (nicotine polacrilex); norepinephrine and dopamine transporters (bupropion)
Addiction Medicine / Smoking Cessation
Small molecule
Live · refreshed every 30 min
Target snapshot
Nicotine polacrilex, Bupropion (Nicotine polacrilex, Bupropion) — University of California, San Francisco. Nicotine polacrilex provides nicotine replacement while bupropion inhibits norepinephrine and dopamine reuptake to reduce cravings and withdrawal symptoms during smoking cessation.
Comparator set
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Nicotine polacrilex, Bupropion TARGET | Nicotine polacrilex, Bupropion | University of California, San Francisco | phase 3 | Nicotine replacement therapy combined with antidepressant | Nicotinic acetylcholine receptors (nicotine polacrilex); norepinephrine and dopamine transporters (bupropion) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Nicotine replacement therapy combined with antidepressant class)
- University of California, San Francisco · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Nicotine polacrilex, Bupropion — Competitive Intelligence Brief. https://druglandscape.com/ci/nicotine-polacrilex-bupropion. Accessed 2026-05-16.
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