Who are Cardene's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Plendil, Coniel, Cinalong, Cleviprex, Sular, Dynacirc.

How often does this brief refresh?

Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-06-10 · How we verify

Cardene — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Cardene (NICARDIPINE) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Dihydropyridine Calcium Channel Blocker. Area: Cardiovascular.

marketed Dihydropyridine Calcium Channel Blocker Voltage-dependent T-type calcium channel subunit alpha-1H Cardiovascular Small molecule Live · refreshed every 30 min

Target snapshot

Cardene (NICARDIPINE) — Hikma Intl Pharms. Cardene works by blocking calcium channels in the heart and blood vessels, which helps to relax and widen blood vessels, reducing blood pressure and heart workload.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Cardene TARGET	NICARDIPINE	Hikma Intl Pharms	marketed	Dihydropyridine Calcium Channel Blocker	Voltage-dependent T-type calcium channel subunit alpha-1H	1988-01-01
Plendil	FELODIPINE	AstraZeneca	marketed	Dihydropyridine Calcium Channel Blocker [EPC]	Voltage-dependent T-type calcium channel subunit alpha-1H	1991-01-01
Coniel	BENIDIPINE		marketed	benidipine	Voltage-dependent T-type calcium channel subunit alpha-1H, Voltage-gated L-type calcium channel
Cinalong	CILNIDIPINE		phase 3	cilnidipine	Voltage-dependent N-type calcium channel subunit alpha-1B, Voltage-dependent T-type calcium channel subunit alpha-1H, Voltage-gated L-type calcium channel
Cleviprex	CLEVIDIPINE	Chiesi	marketed	Dihydropyridine Calcium Channel Blocker [EPC]	Voltage-dependent L-type calcium channel subunit alpha-1C	2008-01-01
Sular	NISOLDIPINE	Azurity	marketed	Dihydropyridine Calcium Channel Blocker [EPC]	Voltage-dependent L-type calcium channel subunit alpha-1C	1995-01-01
Dynacirc	ISRADIPINE	Smithkline Beecham	marketed	Dihydropyridine Calcium Channel Blocker [EPC]	Voltage-dependent L-type calcium channel subunit alpha-1D	1990-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Dihydropyridine Calcium Channel Blocker class)

Hikma Intl Pharms · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Cardene — Competitive Intelligence Brief. https://druglandscape.com/ci/nicardipine. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing