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Neostigmine with glycopyrrolate — Competitive Intelligence Brief
marketed
Acetylcholinesterase inhibitor with anticholinergic agent
Acetylcholinesterase; muscarinic acetylcholine receptors
Neurology
Small molecule
Live · refreshed every 30 min
Target snapshot
Neostigmine with glycopyrrolate (Neostigmine with glycopyrrolate) — The Cleveland Clinic. Neostigmine inhibits acetylcholinesterase to increase acetylcholine levels, while glycopyrrolate blocks muscarinic receptors to counteract cholinergic side effects.
Comparator set (3 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Neostigmine with glycopyrrolate TARGET | Neostigmine with glycopyrrolate | The Cleveland Clinic | marketed | Acetylcholinesterase inhibitor with anticholinergic agent | Acetylcholinesterase; muscarinic acetylcholine receptors | |
| Neostigmine+Glycopyrronium | Neostigmine+Glycopyrronium | Pusan National University Yangsan Hospital | marketed | Acetylcholinesterase inhibitor + Anticholinergic agent | Acetylcholinesterase; Muscarinic acetylcholine receptors | |
| Neostigmine + Glycopyrrolate | Neostigmine + Glycopyrrolate | Merck Sharp & Dohme LLC | marketed | Acetylcholinesterase inhibitor with anticholinergic agent | Acetylcholinesterase (neostigmine); Muscarinic acetylcholine receptors (glycopyrrolate) | |
| Neostigmine w/ Glycopyrrolate | Neostigmine w/ Glycopyrrolate | University of Texas Southwestern Medical Center | marketed | Acetylcholinesterase inhibitor with anticholinergic agent | Acetylcholinesterase (neostigmine); muscarinic acetylcholine receptors (glycopyrrolate) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Acetylcholinesterase inhibitor with anticholinergic agent class)
- Merck Sharp & Dohme LLC · 1 drug in this class
- The Cleveland Clinic · 1 drug in this class
- University of Texas Southwestern Medical Center · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Neostigmine with glycopyrrolate — Competitive Intelligence Brief. https://druglandscape.com/ci/neostigmine-with-glycopyrrolate. Accessed 2026-05-16.
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