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Neostigmine with glycopyrrolate — Competitive Intelligence Brief

Neostigmine with glycopyrrolate (Neostigmine with glycopyrrolate) competitive landscape: 3 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Acetylcholinesterase inhibitor with anticholinergic agent. Area: Neurology.

marketed Acetylcholinesterase inhibitor with anticholinergic agent Acetylcholinesterase; muscarinic acetylcholine receptors Neurology Small molecule Live · refreshed every 30 min

Target snapshot

Neostigmine with glycopyrrolate (Neostigmine with glycopyrrolate) — The Cleveland Clinic. Neostigmine inhibits acetylcholinesterase to increase acetylcholine levels, while glycopyrrolate blocks muscarinic receptors to counteract cholinergic side effects.

Comparator set (3 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Neostigmine with glycopyrrolate TARGET Neostigmine with glycopyrrolate The Cleveland Clinic marketed Acetylcholinesterase inhibitor with anticholinergic agent Acetylcholinesterase; muscarinic acetylcholine receptors
Neostigmine+Glycopyrronium Neostigmine+Glycopyrronium Pusan National University Yangsan Hospital marketed Acetylcholinesterase inhibitor + Anticholinergic agent Acetylcholinesterase; Muscarinic acetylcholine receptors
Neostigmine + Glycopyrrolate Neostigmine + Glycopyrrolate Merck Sharp & Dohme LLC marketed Acetylcholinesterase inhibitor with anticholinergic agent Acetylcholinesterase (neostigmine); Muscarinic acetylcholine receptors (glycopyrrolate)
Neostigmine w/ Glycopyrrolate Neostigmine w/ Glycopyrrolate University of Texas Southwestern Medical Center marketed Acetylcholinesterase inhibitor with anticholinergic agent Acetylcholinesterase (neostigmine); muscarinic acetylcholine receptors (glycopyrrolate)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Acetylcholinesterase inhibitor with anticholinergic agent class)

  1. Merck Sharp & Dohme LLC · 1 drug in this class
  2. The Cleveland Clinic · 1 drug in this class
  3. University of Texas Southwestern Medical Center · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Neostigmine with glycopyrrolate — Competitive Intelligence Brief. https://druglandscape.com/ci/neostigmine-with-glycopyrrolate. Accessed 2026-05-16.

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