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Nelarabine injection — Competitive Intelligence Brief

Nelarabine injection (Nelarabine injection) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Purine analog antimetabolite. Area: Oncology.

phase 3 Purine analog antimetabolite Ribonucleotide reductase; deoxyribonucleotide synthesis pathway Oncology Small molecule Live · refreshed every 30 min

Target snapshot

Nelarabine injection (Nelarabine injection) — Chia Tai Tianqing Pharmaceutical Group Co., Ltd.. Nelarabine is a prodrug that is converted to arabinosyl guanine, which inhibits ribonucleotide reductase and DNA synthesis, leading to apoptosis in T-cell malignancies.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Nelarabine injection TARGET Nelarabine injection Chia Tai Tianqing Pharmaceutical Group Co., Ltd. phase 3 Purine analog antimetabolite Ribonucleotide reductase; deoxyribonucleotide synthesis pathway
Fludarabine (Bayer) Fludarabine (Bayer) Chinese PLA General Hospital marketed Purine analog antimetabolite Ribonucleotide reductase, DNA polymerase
Fludarabine (Flud) Fludarabine (Flud) Technische Universität Dresden marketed Purine analog antimetabolite Ribonucleotide reductase, DNA polymerase
6MP 6MP South China Children's Leukemia Group marketed Purine analog antimetabolite Hypoxanthine-guanine phosphoribosyltransferase (HGPRT), inosine monophosphate dehydrogenase (IMPDH)
mercaptopurine tablet mercaptopurine tablet National Cancer Institute (NCI) phase 3 Purine analog antimetabolite Hypoxanthine-guanine phosphoribosyltransferase (HGPRT), thiopurine methyltransferase (TPMT), and purine synthesis pathway enzymes
Mercaptopurine (Purinethol) Mercaptopurine (Purinethol) Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) phase 3 Purine analog antimetabolite HGPRT (hypoxanthine-guanine phosphoribosyltransferase); inosinate dehydrogenase
Experimental (fludarabine) Experimental (fludarabine) French Innovative Leukemia Organisation phase 3 Purine analog antimetabolite Ribonucleotide reductase, DNA polymerase

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Purine analog antimetabolite class)

  1. Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · 1 drug in this class
  2. Chia Tai Tianqing Pharmaceutical Group Co., Ltd. · 1 drug in this class
  3. Chinese PLA General Hospital · 1 drug in this class
  4. French Innovative Leukemia Organisation · 1 drug in this class
  5. German CLL Study Group · 1 drug in this class
  6. National Cancer Institute (NCI) · 1 drug in this class
  7. South China Children's Leukemia Group · 1 drug in this class
  8. Technische Universität Dresden · 1 drug in this class
  9. University of California, San Francisco · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Nelarabine injection — Competitive Intelligence Brief. https://druglandscape.com/ci/nelarabine-injection. Accessed 2026-05-15.

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