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Ncardipine Hydrochloride Injection — Competitive Intelligence Brief
phase 3
Dihydropyridine calcium channel blocker
L-type voltage-gated calcium channel
Cardiovascular
Small molecule
Live · refreshed every 30 min
Target snapshot
Ncardipine Hydrochloride Injection (Ncardipine Hydrochloride Injection) — Nanjing Yoko Biomedical Co., Ltd.. Nicardipine hydrochloride is a dihydropyridine calcium channel blocker that inhibits calcium influx into vascular smooth muscle cells, causing vasodilation and reducing blood pressure.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Ncardipine Hydrochloride Injection TARGET | Ncardipine Hydrochloride Injection | Nanjing Yoko Biomedical Co., Ltd. | phase 3 | Dihydropyridine calcium channel blocker | L-type voltage-gated calcium channel | |
| Amlodipine plus Metformin | Amlodipine plus Metformin | Third Military Medical University | marketed | Combination therapy: calcium channel blocker + biguanide antidiabetic | L-type voltage-gated calcium channels (amlodipine); AMP-activated protein kinase and mitochondrial glycerophosphate dehydrogenase (metformin) | |
| Levamlodipine besylate | Levamlodipine besylate | Jiangsu Simcere Pharmaceutical Co., Ltd. | marketed | Dihydropyridine calcium channel blocker | L-type voltage-gated calcium channel | |
| Ramipril + Felodipine | Ramipril + Felodipine | Sanofi | marketed | ACE inhibitor + calcium channel blocker combination | Angiotensin-converting enzyme (ACE) and L-type voltage-gated calcium channels | |
| olmesartan medoxomil / amlodipine or azelnidipine | olmesartan medoxomil / amlodipine or azelnidipine | COLM Study Research Organization | marketed | Angiotensin II receptor blocker / Calcium channel blocker combination | Angiotensin II type 1 receptor (AT1R); L-type voltage-gated calcium channels | |
| Losartan (+) amlodipine | Losartan (+) amlodipine | Organon and Co | marketed | Angiotensin II receptor blocker + calcium channel blocker combination | AT1 receptor (losartan); L-type voltage-gated calcium channel (amlodipine) | |
| nifedipine CR tablets (Adalat) | nifedipine CR tablets (Adalat) | Shanghai Shyndec Pharmaceutical Co., Ltd. | marketed | Calcium channel blocker (dihydropyridine) | L-type voltage-gated calcium channel |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Dihydropyridine calcium channel blocker class)
- Bayer · 1 drug in this class
- CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd. · 1 drug in this class
- Haseki Training and Research Hospital · 1 drug in this class
- Jiangsu Simcere Pharmaceutical Co., Ltd. · 1 drug in this class
- Korea University Guro Hospital · 1 drug in this class
- Nanjing Yoko Biomedical Co., Ltd. · 1 drug in this class
- Organon and Co · 1 drug in this class
- Pfizer Inc. · 1 drug in this class
- University Hospital Hradec Kralove · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Ncardipine Hydrochloride Injection — Competitive Intelligence Brief. https://druglandscape.com/ci/ncardipine-hydrochloride-injection. Accessed 2026-05-16.
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