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Last reviewed 2026-06-10 · How we verify

TYRUKO — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

TYRUKO (NATALIZUMAB-SZTN) competitive landscape: 2 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Integrin Receptor Antagonist [EPC]. Area: Other.

marketed Integrin Receptor Antagonist [EPC] Other Live · refreshed every 30 min

Target snapshot

TYRUKO (NATALIZUMAB-SZTN) — SANDOZ INC.

Comparator set (2 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
TYRUKO TARGET	NATALIZUMAB-SZTN	SANDOZ INC	marketed	Integrin Receptor Antagonist [EPC]
Tysabri	NATALIZUMAB	Biogen Idec	marketed	Integrin Receptor Antagonist [EPC]	α4β1 and α4β7 integrins	2004-01-01
Entyvio	vedolizumab	Takeda	marketed	Integrin Receptor Antagonist [EPC]	Integrin alpha-4/beta-7

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Integrin Receptor Antagonist [EPC] class)

Biogen Idec · 1 drug in this class
SANDOZ INC · 1 drug in this class
Takeda · 1 drug in this class

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Cite this brief

Drug Landscape (2026). TYRUKO — Competitive Intelligence Brief. https://druglandscape.com/ci/natalizumab-sztn. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing