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NAs+IFN-α — Competitive Intelligence Brief
marketed
Antiviral combination therapy
Hepatitis B virus reverse transcriptase; interferon-alpha receptor signaling
Virology/Hepatology
Small molecule
Live · refreshed every 30 min
Target snapshot
NAs+IFN-α (NAs+IFN-α) — Beijing 302 Hospital. NAs+IFN-α combines nucleos(t)ide analogues with interferon-alpha to suppress hepatitis B virus replication and enhance antiviral immune response.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| NAs+IFN-α TARGET | NAs+IFN-α | Beijing 302 Hospital | marketed | Antiviral combination therapy | Hepatitis B virus reverse transcriptase; interferon-alpha receptor signaling | |
| F: Peg-interferon alpha-2a & Ribavirin | F: Peg-interferon alpha-2a & Ribavirin | Kaohsiung Medical University Chung-Ho Memorial Hospital | marketed | Antiviral combination therapy | Interferon-alpha receptor; Hepatitis C virus RNA-dependent RNA polymerase | |
| C: Peg-interferon alpha-2a & Ribavirin | C: Peg-interferon alpha-2a & Ribavirin | Kaohsiung Medical University Chung-Ho Memorial Hospital | marketed | Antiviral combination therapy | Interferon-alpha receptor; HCV RNA-dependent RNA polymerase | |
| E: Peg-interferon alpha-2a & Ribavirin | E: Peg-interferon alpha-2a & Ribavirin | Kaohsiung Medical University Chung-Ho Memorial Hospital | marketed | Antiviral combination therapy | Interferon-alpha receptor; viral RNA-dependent RNA polymerase | |
| Peg-IFN + WB RBV for 48 weeks | Peg-IFN + WB RBV for 48 weeks | National Taiwan University Hospital | marketed | Antiviral combination therapy | Interferon-alpha receptor; HCV RNA polymerase | |
| interferon α 2b + ribavirin | interferon α 2b + ribavirin | The Immunobiological Technology Institute (Bio-Manguinhos) / Oswaldo Cruz Foundation (Fiocruz) | marketed | Antiviral combination therapy | Interferon-α receptor; viral RNA-dependent RNA polymerase | |
| Peg-IFN + LD RBV for 24 weeks | Peg-IFN + LD RBV for 24 weeks | National Taiwan University Hospital | marketed | Antiviral combination therapy | Interferon alpha receptor; HCV RNA-dependent RNA polymerase |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Antiviral combination therapy class)
- Kaohsiung Medical University Chung-Ho Memorial Hospital · 6 drugs in this class
- National Taiwan University Hospital · 6 drugs in this class
- Casa Sollievo della Sofferenza IRCCS · 1 drug in this class
- Hepatitis Resource Network · 1 drug in this class
- Hospices Civils de Lyon · 1 drug in this class
- MTI Medical Private Limited, Pakistan · 1 drug in this class
- Pacific Health Foundation · 1 drug in this class
- RedHill Biopharma Limited · 1 drug in this class
- Sherief Abd-Elsalam · 1 drug in this class
- The Immunobiological Technology Institute (Bio-Manguinhos) / Oswaldo Cruz Foundation (Fiocruz) · 1 drug in this class
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Cite this brief
Drug Landscape (2026). NAs+IFN-α — Competitive Intelligence Brief. https://druglandscape.com/ci/nas-ifn. Accessed 2026-05-13.
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