Last reviewed · How we verify
NALIRIFOX plus targeted therapy — Competitive Intelligence Brief
phase 3
Combination chemotherapy with targeted therapy
Topoisomerase I, thymidylate synthase, and variable molecular targets depending on targeted therapy partner
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
NALIRIFOX plus targeted therapy (NALIRIFOX plus targeted therapy) — Shanghai Zhongshan Hospital. NALIRIFOX is a combination of nal-IRI (irinotecan liposomal) and 5-fluorouracil that inhibits topoisomerase I and nucleotide synthesis, combined with targeted therapy to enhance anti-tumor activity.
Comparator set
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| NALIRIFOX plus targeted therapy TARGET | NALIRIFOX plus targeted therapy | Shanghai Zhongshan Hospital | phase 3 | Combination chemotherapy with targeted therapy | Topoisomerase I, thymidylate synthase, and variable molecular targets depending on targeted therapy partner |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Combination chemotherapy with targeted therapy class)
- Shanghai Zhongshan Hospital · 1 drug in this class
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Cite this brief
Drug Landscape (2026). NALIRIFOX plus targeted therapy — Competitive Intelligence Brief. https://druglandscape.com/ci/nalirifox-plus-targeted-therapy. Accessed 2026-05-16.
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