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Naftin 1% Cream — Competitive Intelligence Brief

Naftin 1% Cream (Naftin 1% Cream) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Allylamine antifungal. Area: Dermatology.

phase 3 Allylamine antifungal Squalene epoxidase Dermatology Small molecule Live · refreshed every 30 min

Target snapshot

Naftin 1% Cream (Naftin 1% Cream) — Merz North America, Inc.. Naftin (naftifine) is a topical antifungal that inhibits fungal sterol synthesis by blocking squalene epoxidase, disrupting the fungal cell membrane.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Naftin 1% Cream TARGET Naftin 1% Cream Merz North America, Inc. phase 3 Allylamine antifungal Squalene epoxidase
NAFT600 (pediatric) NAFT600 (pediatric) Merz North America, Inc. marketed Topical antifungal (allylamine) Squalene epoxidase (fungal)
Lotrimin Ultra® Lotrimin Ultra® Sun Pharmaceutical Industries, Inc. marketed Allylamine antifungal Squalene epoxidase
Jublia® Jublia® Dong-A ST Co., Ltd. marketed Azole antifungal Squalene epoxidase (fungal)
Tavaborole 5% Topical Solution Tavaborole 5% Topical Solution Pfizer marketed Benzoxaborole antifungal Squalene epoxidase
NAFT500 (pediatric) NAFT500 (pediatric) Merz North America, Inc. marketed Allylamine antifungal Squalene epoxidase
Terbinafine Tablets Terbinafine Tablets Oregon Health and Science University marketed Allylamine antifungal Squalene epoxidase

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Allylamine antifungal class)

  1. Merz North America, Inc. · 3 drugs in this class
  2. Sun Pharmaceutical Industries, Inc. · 2 drugs in this class
  3. Bayer · 1 drug in this class
  4. Oregon Health and Science University · 1 drug in this class
  5. Pak Emirates Military Hospital · 1 drug in this class
  6. Novartis · 1 drug in this class
  7. Galderma R&D · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Naftin 1% Cream — Competitive Intelligence Brief. https://druglandscape.com/ci/naftin-1-cream. Accessed 2026-05-16.

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