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N2O gas vs ketamine — Competitive Intelligence Brief
marketed
NMDA receptor antagonist (dissociative anesthetic)
NMDA receptor
Anesthesia / Analgesia
Small molecule
Live · refreshed every 30 min
Target snapshot
N2O gas vs ketamine (N2O gas vs ketamine) — Seoul National University Hospital. This is a comparative study of two dissociative anesthetics—nitrous oxide (N2O) and ketamine—which work by blocking NMDA receptors to produce anesthesia and analgesia.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| N2O gas vs ketamine TARGET | N2O gas vs ketamine | Seoul National University Hospital | marketed | NMDA receptor antagonist (dissociative anesthetic) | NMDA receptor | |
| Namenda | MEMANTINE | AbbVie | marketed | N-methyl-D-aspartate Receptor Antagonist | Glutamate NMDA receptor; GRIN1/GRIN2A | 2003-01-01 |
| Felbatol | FELBAMATE | Mylan Speciality Lp | marketed | Anti-epileptic Agent [EPC] | NMDA receptor-ionophore complex | 1993-01-01 |
| QUINIDINE | QUINIDINE | marketed | sigma-1 receptor, NMDA receptor, CYP2D6 | 1950-01-01 | ||
| Methadone Hydrochloride | METHADONE | Specgx Llc | marketed | Opioid Agonist | mu-opioid receptors, NMDA receptor | 1947-01-01 |
| S (+) Ketamine | S (+) Ketamine | Asker & Baerum Hospital | marketed | NMDA receptor antagonist | NMDA receptor | |
| Saline + Ketamine | Saline + Ketamine | Ullevaal University Hospital | marketed | NMDA receptor antagonist / Dissociative anesthetic | NMDA receptor (glutamate-gated ion channel) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (NMDA receptor antagonist (dissociative anesthetic) class)
- Seoul National University Hospital · 1 drug in this class
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Cite this brief
Drug Landscape (2026). N2O gas vs ketamine — Competitive Intelligence Brief. https://druglandscape.com/ci/n2o-gas-vs-ketamine. Accessed 2026-05-16.
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