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MRG002 — Competitive Intelligence Brief

MRG002 (MRG002) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Bispecific antibody. Area: Oncology.

phase 3 Bispecific antibody Oncology Small molecule Live · refreshed every 30 min

Target snapshot

MRG002 (MRG002) — Shanghai Miracogen Inc.. MRG002 is a bispecific antibody that simultaneously engages tumor-associated antigens and immune effector cells to enhance anti-tumor immunity.

Comparator set (6 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
MRG002 TARGET MRG002 Shanghai Miracogen Inc. phase 3 Bispecific antibody
Elrexfio elranatamab Pfizer marketed Bispecific antibody BCMA (B-cell maturation antigen) on plasma cells, plasmablasts, and multiple myeloma cells; CD3 on T-cells 2023-01-01
Elrexfio Elranatamab Pfizer marketed Bispecific antibody BCMA (B-cell maturation antigen) on plasma cells, plasmablasts, and multiple myeloma cells; CD3 on T-cells 2023-01-01
Elrantamab elrantamab Pfizer marketed Bispecific Antibody BCMA (B-cell maturation antigen)
HZT-501 HZT-501 Amgen phase 3 Bispecific antibody
IBI354 IBI354 Innovent Biologics (Suzhou) Co. Ltd. phase 3 Bispecific antibody; PD-1/TGF-β inhibitor PD-1 and TGF-β
Ivonescimab, docetaxel Ivonescimab, docetaxel Akeso phase 3 PD-L1/CTLA-4 bispecific antibody + taxane chemotherapy PD-L1, CTLA-4 (ivonescimab); β-tubulin (docetaxel)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Bispecific antibody class)

  1. Shanghai Miracogen Inc. · 3 drugs in this class
  2. Atom Therapeutics Co., Ltd · 2 drugs in this class
  3. Pfizer · 2 drugs in this class
  4. Allergan · 1 drug in this class
  5. AstraZeneca · 1 drug in this class
  6. BioNTech SE · 1 drug in this class
  7. DualityBio Inc. · 1 drug in this class
  8. Coherus Oncology, Inc. · 1 drug in this class
  9. Genmab · 1 drug in this class
  10. Amgen · 1 drug in this class

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Cite this brief

Drug Landscape (2026). MRG002 — Competitive Intelligence Brief. https://druglandscape.com/ci/mrg002. Accessed 2026-05-13.

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