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MPL-001 (CBD: THC 25:1) — Competitive Intelligence Brief

MPL-001 (CBD: THC 25:1) (MPL-001 (CBD: THC 25:1)) competitive landscape: 5 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Cannabinoid combination.

phase 3 Cannabinoid combination CB1 receptor, CB2 receptor, 5-HT1A receptor, TRPV1 receptor Small molecule Live · refreshed every 30 min

Target snapshot

MPL-001 (CBD: THC 25:1) (MPL-001 (CBD: THC 25:1)) — McMaster University. MPL-001 is a cannabinoid combination product that modulates endocannabinoid signaling through CBD and THC at a 25:1 ratio to produce therapeutic effects.

Comparator set (5 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
MPL-001 (CBD: THC 25:1) TARGET MPL-001 (CBD: THC 25:1) McMaster University phase 3 Cannabinoid combination CB1 receptor, CB2 receptor, 5-HT1A receptor, TRPV1 receptor
MediCabilis CBD Oil MediCabilis CBD Oil Gold Coast Hospital and Health Service marketed Cannabinoid CB1 receptor, CB2 receptor, 5-HT1A receptor, TRPV1 receptor (multiple targets)
Cannabidiol (CBD) Oil Capsules Cannabidiol (CBD) Oil Capsules McMaster University phase 3 Phytocannabinoid CB1 receptor, CB2 receptor, 5-HT1A receptor, TRPV1 receptor (multi-target)
Cannabidiol (CBD) Extract Cannabidiol (CBD) Extract Milton S. Hershey Medical Center phase 3 Cannabinoid receptor modulator CB1 receptor, CB2 receptor, 5-HT1A receptor, TRPV1 receptor
Placebo Matched to Low-Dose Cannabidiol Placebo Matched to Low-Dose Cannabidiol Wayne State University phase 3 Cannabinoid CB1 receptor, CB2 receptor, 5-HT1A receptor, TRPV1 receptor
Moderate-Dose Cannabidiol Moderate-Dose Cannabidiol Wayne State University phase 3 Cannabinoid CB1 receptor, CB2 receptor, 5-HT1A receptor, TRPV1 receptor

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Cannabinoid combination class)

  1. McMaster University · 1 drug in this class

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Cite this brief

Drug Landscape (2026). MPL-001 (CBD: THC 25:1) — Competitive Intelligence Brief. https://druglandscape.com/ci/mpl-001-cbd-thc-25-1. Accessed 2026-05-16.

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