Who are Singulair's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Singulair, montelukast (Singulair), MK0476; montelukast sodium, Montelukast (drug), montelukast (MON), Comparator: Montelukast.

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Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-14 · How we verify

Singulair — Competitive Intelligence Brief

Singulair (montelukast) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Leukotriene receptor antagonist (LTRA). Area: Neuroscience.

marketed Leukotriene receptor antagonist (LTRA) Cytochrome P450 2C8, Adenosine receptor A3, Cysteinyl leukotriene receptor 2 Neuroscience Small molecule Live · refreshed every 30 min

Target snapshot

Singulair (montelukast) — Merck & Co.. Leukotriene receptor antagonist (LTRA) that blocks CysLT1 receptors, reducing bronchoconstriction, mucus production, and airway inflammation.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Singulair TARGET	montelukast	Merck & Co.	marketed	Leukotriene receptor antagonist (LTRA)	Cytochrome P450 2C8, Adenosine receptor A3, Cysteinyl leukotriene receptor 2	1998-02-20
Singulair	Singulair	Genuine Research Center, Egypt	marketed		Cytochrome P450 2C8, Adenosine receptor A3, Cysteinyl leukotriene receptor 2
montelukast (Singulair)	montelukast (Singulair)	University of Bologna	marketed	Cysteinyl leukotriene receptor antagonist (LTRA)	CysLT1 receptor
MK0476; montelukast sodium	MK0476; montelukast sodium	Organon and Co	marketed	Cysteinyl leukotriene receptor antagonist (LTRA)	CysLT1 (cysteinyl leukotriene receptor 1)
Montelukast (drug)	Montelukast (drug)	Firestone Institute for Respiratory Health	marketed	Cysteinyl leukotriene receptor antagonist (LTRA)	CysLT1 receptor
montelukast (MON)	montelukast (MON)	GlaxoSmithKline	marketed	Cysteinyl leukotriene receptor antagonist (LTRA)	CysLT1 receptor
Comparator: Montelukast	Comparator: Montelukast	Organon and Co	marketed	Cysteinyl leukotriene receptor antagonist (LTRA)	CysLT1 (cysteinyl leukotriene receptor 1)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Leukotriene receptor antagonist (LTRA) class)

Merck & Co. · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Singulair — Competitive Intelligence Brief. https://druglandscape.com/ci/montelukast. Accessed 2026-05-14.

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