Last reviewed · How we verify
modified FOLFOX6 + bevacizumab — Competitive Intelligence Brief
phase 3
Chemotherapy combination + monoclonal antibody
DNA (chemotherapy); VEGF (bevacizumab)
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
modified FOLFOX6 + bevacizumab (modified FOLFOX6 + bevacizumab) — Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD). Modified FOLFOX6 chemotherapy combined with bevacizumab inhibits tumor cell division and blocks new blood vessel formation to starve tumors of nutrients.
Comparator set (3 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| modified FOLFOX6 + bevacizumab TARGET | modified FOLFOX6 + bevacizumab | Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD) | phase 3 | Chemotherapy combination + monoclonal antibody | DNA (chemotherapy); VEGF (bevacizumab) | |
| FOLFIRI + cetuximab | FOLFIRI + cetuximab | Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD) | marketed | Chemotherapy combination + monoclonal antibody | EGFR (epidermal growth factor receptor); DNA (via FOLFIRI) | |
| Folfox with avastin | Folfox with avastin | Sherief Abd-Elsalam | phase 3 | Chemotherapy combination + monoclonal antibody (anti-VEGF) | DNA (chemotherapy); VEGF (bevacizumab) | |
| FOLFOXIRI + Bevacizumab | FOLFOXIRI + Bevacizumab | Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD) | phase 3 | Chemotherapy combination + monoclonal antibody (anti-VEGF) | DNA (chemotherapy); VEGF (bevacizumab) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Chemotherapy combination + monoclonal antibody class)
- Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD) · 2 drugs in this class
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Cite this brief
Drug Landscape (2026). modified FOLFOX6 + bevacizumab — Competitive Intelligence Brief. https://druglandscape.com/ci/modified-folfox6-bevacizumab. Accessed 2026-05-17.
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