Who are MK0966; rofecoxib's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Cox2 inhibitor (Celecoxib), parecoxib, valdecoxib, etoricoxib, Oral Vioxx (Rofecoxib), MK0966 / Duration of Treatment: 1 Days.

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Last reviewed 2026-06-09 · How we verify

MK0966; rofecoxib — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

MK0966; rofecoxib (MK0966; rofecoxib) competitive landscape: 4 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: COX-2 selective inhibitor (coxib). Area: Rheumatology / Pain Management.

marketed COX-2 selective inhibitor (coxib) COX-2 (cyclooxygenase-2) Rheumatology / Pain Management Small molecule Live · refreshed every 30 min

Target snapshot

MK0966; rofecoxib (MK0966; rofecoxib) — Merck Sharp & Dohme LLC. Rofecoxib selectively inhibits cyclooxygenase-2 (COX-2), reducing prostaglandin production to decrease inflammation and pain.

Comparator set (4 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
MK0966; rofecoxib TARGET	MK0966; rofecoxib	Merck Sharp & Dohme LLC	marketed	COX-2 selective inhibitor (coxib)	COX-2 (cyclooxygenase-2)
Cox2 inhibitor (Celecoxib)	Cox2 inhibitor (Celecoxib)	Seoul National University Hospital	marketed	COX-2 selective inhibitor (coxib)	COX-2 (Cyclooxygenase-2)
parecoxib, valdecoxib, etoricoxib	parecoxib, valdecoxib, etoricoxib	Asker & Baerum Hospital	marketed	COX-2 selective inhibitor (coxib)	COX-2 (cyclooxygenase-2)
Oral Vioxx (Rofecoxib)	Oral Vioxx (Rofecoxib)	Chinese University of Hong Kong	phase 3	COX-2 selective inhibitor (coxib)	COX-2 (Cyclooxygenase-2)
MK0966 / Duration of Treatment: 1 Days	MK0966 / Duration of Treatment: 1 Days	Merck Sharp & Dohme LLC	phase 3	COX-2 selective inhibitor (coxib)	COX-2 (Cyclooxygenase-2)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (COX-2 selective inhibitor (coxib) class)

Merck Sharp & Dohme LLC · 2 drugs in this class
Asker & Baerum Hospital · 1 drug in this class
Chinese University of Hong Kong · 1 drug in this class
Seoul National University Hospital · 1 drug in this class

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Cite this brief

Drug Landscape (2026). MK0966; rofecoxib — Competitive Intelligence Brief. https://druglandscape.com/ci/mk0966-rofecoxib. Accessed 2026-06-09.

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