Who are MK0524A, /Duration of Treatment : 4 Weeks's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Niacin plus laropiprant, Slo-Niacin, atorvastatin, Statin plus niacin ER/laropiprant, nicotinic acid/laropiprant, Nicotinic acid (niacin), Niacin Extended Release/Lovastatin.

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Last reviewed 2026-05-18 · How we verify

MK0524A, /Duration of Treatment : 4 Weeks — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

MK0524A, /Duration of Treatment : 4 Weeks (MK0524A, /Duration of Treatment : 4 Weeks) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: GPR109A agonist. Area: Cardiovascular.

phase 3 GPR109A agonist GPR109A Cardiovascular Small molecule Live · refreshed every 30 min

Target snapshot

MK0524A, /Duration of Treatment : 4 Weeks (MK0524A, /Duration of Treatment : 4 Weeks) — Merck Sharp & Dohme LLC. MK0524A is a niacin receptor agonist that activates GPR109A to raise HDL cholesterol and lower triglycerides.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
MK0524A, /Duration of Treatment : 4 Weeks TARGET	MK0524A, /Duration of Treatment : 4 Weeks	Merck Sharp & Dohme LLC	phase 3	GPR109A agonist	GPR109A
Niacin plus laropiprant	Niacin plus laropiprant	Institut Investigacio Sanitaria Pere Virgili	marketed	Lipid-modifying agent combination	DP1 receptor (laropiprant component); niacin acts on GPR109A and other pathways
Slo-Niacin, atorvastatin	Slo-Niacin, atorvastatin	University of Washington	marketed	Niacin derivative and HMG-CoA reductase inhibitor (statin combination)	Nicotinic acid receptor (GPR109A) and HMG-CoA reductase
Statin plus niacin ER/laropiprant	Statin plus niacin ER/laropiprant	University of Ioannina	marketed	Statin combined with niacin ER and DP1 antagonist	HMG-CoA reductase (statin component); GPR109A/PUMA-G (niacin component); DP1 receptor (laropiprant component)
nicotinic acid/laropiprant	nicotinic acid/laropiprant	Manchester University NHS Foundation Trust	marketed	Lipid-modifying agent / Antilipemic	GPR109A receptor (laropiprant component); nicotinic acid acts on multiple lipid metabolism pathways
Nicotinic acid (niacin)	Nicotinic acid (niacin)	Charite University, Berlin, Germany	marketed	Lipid-modifying agent; B vitamin	GPR109A (HM74A receptor)
Niacin Extended Release/Lovastatin	Niacin Extended Release/Lovastatin	In His Image	marketed	Statin/Niacin combination; Lipid-modifying agent	HMG-CoA reductase (lovastatin); GPR109A/PUMA-G receptor (niacin)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (GPR109A agonist class)

Merck Sharp & Dohme LLC · 1 drug in this class

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Cite this brief

Drug Landscape (2026). MK0524A, /Duration of Treatment : 4 Weeks — Competitive Intelligence Brief. https://druglandscape.com/ci/mk0524a-duration-of-treatment-4-weeks. Accessed 2026-05-18.

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