Mixture of three Bifidobacteria — Competitive Intelligence Brief

Mixture of three Bifidobacteria (Mixture of three Bifidobacteria) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Probiotic. Area: Gastroenterology.

marketed Probiotic Gastroenterology Small molecule

Target snapshot

Mixture of three Bifidobacteria (Mixture of three Bifidobacteria) — Federico II University. A mixture of three Bifidobacteria strains restores beneficial gut microbiota composition to promote intestinal health and immune function.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Mixture of three Bifidobacteria TARGET	Mixture of three Bifidobacteria	Federico II University	marketed	Probiotic
E. coli Nissle suspension	E. coli Nissle suspension	University of Hohenheim	marketed	Live biotherapeutic product (probiotic)
Mesalazine plus Lactobacillus casei	Mesalazine plus Lactobacillus casei	Hospital Cristo Re	marketed	Anti-inflammatory agent plus probiotic combination
"AS-Probionorm"	"AS-Probionorm"	Industrial Microbiology LLP	marketed	Probiotic
Akkermansia muciniphila + Infliximab	Akkermansia muciniphila + Infliximab	Chinese Medical Association	marketed	Combination therapy: probiotic + TNF-α inhibitor	TNF-α (infliximab component); gut microbiota modulation (Akkermansia muciniphila component)
Probiotic Vivomixx	Probiotic Vivomixx	University of Milan	marketed	Probiotic
Clotrimazole vaginal tablets+ Lactobacillus	Clotrimazole vaginal tablets+ Lactobacillus	Peking University Shenzhen Hospital	marketed	Antifungal + probiotic combination	Fungal lanosterol 14α-demethylase (CYP51); Lactobacillus competitive exclusion and microbiota restoration

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Probiotic class)

1. BioBalance Corporation · 1 drug in this class
2. Biocodex · 1 drug in this class
3. CD Pharma India Pvt. Ltd. · 1 drug in this class
4. CHU de Quebec-Universite Laval · 1 drug in this class
5. Chuncheon Sacred Heart Hospital · 1 drug in this class
6. Dow University of Health Sciences · 1 drug in this class
7. Federico II University · 1 drug in this class
8. Fundación Hospital de Pediatría Prof. Dr. Juan P. Garrahan · 1 drug in this class
9. GWT-TUD GmbH · 1 drug in this class
10. Aga Khan University · 1 drug in this class