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Novantrone — Competitive Intelligence Brief
marketed
Topoisomerase Inhibitor
Serine/threonine-protein kinase pim-1
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
Novantrone (MITOXANTRONE). Novantrone works by interfering with the enzyme topoisomerase, which is necessary for DNA replication and cell division.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Novantrone TARGET | MITOXANTRONE | marketed | Topoisomerase Inhibitor | Serine/threonine-protein kinase pim-1 | 1987-01-01 | |
| Colcrys | COLCHICINE | Scilex Pharms | marketed | Alkaloid [EPC] | Serine/threonine-protein kinase pim-1 | 1961-01-01 |
| Ellence | EPIRUBICIN | Pfizer | marketed | Anthracycline Topoisomerase Inhibitor | Tyrosine-protein kinase Fyn | 1999-01-01 |
| Camptosar | irinotecan | Pfizer | marketed | Topoisomerase Inhibitor | topoisomerase I | 1996-01-01 |
| Camptosar | Irinotecan Hydrochloride | Pfizer | marketed | Topoisomerase Inhibitor | Acetylcholinesterase | 1996-01-01 |
| Camptosar | onivyde | Pfizer | marketed | Topoisomerase Inhibitor | Acetylcholinesterase | 1996-01-01 |
| Idamycin Pfs | IDARUBICIN HYDROCHLORIDE | marketed | Anthracycline Topoisomerase Inhibitor | DNA, topoisomerase II | 1990-01-01 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
- — Camptosar · 8329213 · US
- — Camptosar · 8329213 · Compound · US
- — Camptosar · 8147867 · Compound · US
- — Camptosar · 8147867 · US
- — Camptosar · 9364473 · US
- — Camptosar · 9452162 · US
- — Camptosar · 9492442 · US
- — Camptosar · 9717724 · US
- — Camptosar · 9717724 · Method of Use · US
- — Camptosar · 9364473 · Method of Use · US
- — Camptosar · 12364691 · Method of Use · US
- — Camptosar · 11369597 · Method of Use · US
- — Camptosar · 9339497 · Method of Use · US
- — Camptosar · 9452162 · Method of Use · US
- — Camptosar · 9492442 · Method of Use · US
- — Camptosar · 10980795 · US
- — Camptosar · 11369597 · US
- — Camptosar · 9339497 · US
- — Camptosar · 10980795 · Method of Use · US
- — Camptosar · 11344552 · Method of Use · US
- — Camptosar · 10456360 · US
- — Camptosar · 10993914 · US
- — Camptosar · 12059497 · Formulation · US
- — Camptosar · 10456360 · Formulation · US
- — Camptosar · 10993914 · Formulation · US
Sponsor landscape (Topoisomerase Inhibitor class)
- Pfizer · 3 drugs in this class
- · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Novantrone — Competitive Intelligence Brief. https://druglandscape.com/ci/mitoxantrone. Accessed 2026-05-13.
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