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Midazolam (sedative) — Competitive Intelligence Brief
marketed
Benzodiazepine
GABA-A receptor
Neurology / Anesthesia
Small molecule
Live · refreshed every 30 min
Target snapshot
Midazolam (sedative) (Midazolam (sedative)) — Technische Universität Dresden. Midazolam is a benzodiazepine that enhances the inhibitory effects of GABA at GABA-A receptors in the central nervous system, producing sedation and anxiolysis.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Midazolam (sedative) TARGET | Midazolam (sedative) | Technische Universität Dresden | marketed | Benzodiazepine | GABA-A receptor | |
| Zulresso | BREXANOLONE | Sage Therap | marketed | Neuroactive Steroid Gamma-Aminobutyric Acid A Receptor Positive Modulator | GABA-A receptor alpha-1/beta-2/gamma-2 | 2019-01-01 |
| Onfi | CLOBAZAM | Lundbeck Pharms Llc | marketed | Benzodiazepine [EPC] | GABA-A receptor alpha-1/beta-2/gamma-2 | 2011-01-01 |
| Lusedra | FOSPROPOFOL | marketed | fospropofol | GABA-A receptor | 2008-01-01 | |
| Campral | ACAMPROSATE | Allergan/AbbVie | marketed | acamprosate | GABA-A receptor alpha-1/beta-3/gamma-2 | 2004-01-01 |
| Sonata | ZALEPLON | Pfizer | marketed | gamma-Aminobutyric Acid A Receptor Agonist [EPC] | GABA-A receptor alpha-1/beta-2/gamma-2 | 1999-01-01 |
| Suprane | DESFLURANE | Baxter | marketed | General Anesthetic [EPC] | GABA-A receptor; anion channel | 1992-01-01 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
- — Onfi · 12403090 · Formulation · US
- — Onfi · 12290597 · Formulation · US
- — Onfi · 11541002 · Formulation · US
Sponsor landscape (Benzodiazepine class)
- Hamad Medical Corporation · 3 drugs in this class
- Lundbeck LLC · 2 drugs in this class
- UCB Biopharma SRL · 2 drugs in this class
- Universitaire Ziekenhuizen KU Leuven · 2 drugs in this class
- Bausch Health · 1 drug in this class
- Centro Medico Nacional La Raza, IMSS · 1 drug in this class
- Assaf-Harofeh Medical Center · 1 drug in this class
- Daegu Catholic University Medical Center · 1 drug in this class
- B.P. Koirala Institute of Health Sciences · 1 drug in this class
- Consorci Sanitari de l'Anoia · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Midazolam (sedative) — Competitive Intelligence Brief. https://druglandscape.com/ci/midazolam-sedative. Accessed 2026-05-15.
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