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Last reviewed 2026-05-15 · How we verify

Metopirone — Competitive Intelligence Brief

Metopirone (METYRAPONE) competitive landscape: 2 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Adrenal Steroid Synthesis Inhibitor [EPC]. Area: Metabolic.

marketed Adrenal Steroid Synthesis Inhibitor [EPC] Cytochrome P450 11B1, mitochondrial Metabolic Small molecule Live · refreshed every 30 min

Target snapshot

Metopirone (METYRAPONE) — Esteve. Metopirone works by inhibiting the enzyme responsible for converting a precursor into cortisol, effectively reducing cortisol production.

Comparator set (2 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Metopirone TARGET	METYRAPONE	Esteve	marketed	Adrenal Steroid Synthesis Inhibitor [EPC]	Cytochrome P450 11B1, mitochondrial	1961-01-01
Zytiga	Zytiga	Bukwang Pharmaceutical	marketed		Cytochrome P450 11B2, mitochondrial, Androgen receptor, Cytochrome P450 11B1, mitochondrial
Cytadren	AMINOGLUTETHIMIDE	Novartis	marketed	Adrenal Steroid Synthesis Inhibitor	Aromatase	1980-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Adrenal Steroid Synthesis Inhibitor [EPC] class)

Esteve · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Metopirone — Competitive Intelligence Brief. https://druglandscape.com/ci/metyrapone. Accessed 2026-05-15.

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