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Metvix and conventional PDT — Competitive Intelligence Brief
phase 3
Photosensitizing agent
Protoporphyrin IX (via aminolevulinic acid pathway)
Oncology / Dermatology
Small molecule
Live · refreshed every 30 min
Target snapshot
Metvix and conventional PDT (Metvix and conventional PDT) — Galderma R&D. Metvix is a photosensitizing agent that accumulates in abnormal skin cells and, when activated by light in photodynamic therapy (PDT), generates reactive oxygen species to destroy lesions.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Metvix and conventional PDT TARGET | Metvix and conventional PDT | Galderma R&D | phase 3 | Photosensitizing agent | Protoporphyrin IX (via aminolevulinic acid pathway) | |
| Verteporfin for injection | Verteporfin for injection | Novartis | marketed | Photosensitizing agent | Lipoprotein receptors on neovascular endothelial cells | |
| Verteporfin Photodynamic Therapy | Verteporfin Photodynamic Therapy | Novartis | marketed | Photosensitizing agent | Lipoprotein receptors on neovascular endothelial cells | |
| Methyl Aminolaevulinate 16% Cream | Methyl Aminolaevulinate 16% Cream | Galderma R&D | marketed | Photosensitizing agent | Protoporphyrin IX (via aminolaevulinic acid pathway) | |
| verteporfin PDT | verteporfin PDT | QLT Inc. | marketed | Photosensitizing agent | Lipoprotein receptors on neovascular endothelial cells | |
| MAL | MAL | Photocure | marketed | Photosensitizing agent | Protoporphyrin IX (via aminolevulinic acid pathway) | |
| Levulan® Kerastick® | Levulan® Kerastick® | Medical Dermatology Specialists | marketed | Photosensitizing agent | Protoporphyrin IX (photodynamic therapy precursor) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Photosensitizing agent class)
- Galderma R&D · 4 drugs in this class
- Novartis · 2 drugs in this class
- QLT Inc. · 2 drugs in this class
- Medical Dermatology Specialists · 1 drug in this class
- Photocure · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Metvix and conventional PDT — Competitive Intelligence Brief. https://druglandscape.com/ci/metvix-and-conventional-pdt. Accessed 2026-05-17.
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