Who are Metoprolol (MET)'s main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Onoact, Betaxon, Genesa, Zebeta, Levadil, Optipranolol.

How often does this brief refresh?

Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Subscribe to /feed/ci/metoprolol-met.xml in any RSS reader (Feedly, Inoreader, NewsBlur). Every regulatory action, trial readout, or patent event lands in your feed automatically.

Last reviewed 2026-05-14 · How we verify

Metoprolol (MET) — Competitive Intelligence Brief

Metoprolol (MET) (Metoprolol (MET)) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Beta-1 selective adrenergic receptor antagonist (beta-blocker). Area: Cardiovascular.

marketed Beta-1 selective adrenergic receptor antagonist (beta-blocker) Beta-1 adrenergic receptor Cardiovascular Small molecule Live · refreshed every 30 min

Target snapshot

Metoprolol (MET) (Metoprolol (MET)) — Tel-Aviv Sourasky Medical Center. Metoprolol is a beta-1 selective adrenergic receptor antagonist that reduces heart rate, blood pressure, and cardiac workload.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Metoprolol (MET) TARGET	Metoprolol (MET)	Tel-Aviv Sourasky Medical Center	marketed	Beta-1 selective adrenergic receptor antagonist (beta-blocker)	Beta-1 adrenergic receptor
Onoact	LANDIOLOL	Aop Hlth Us	marketed	landiolol	Beta-1 adrenergic receptor	2024-01-01
Betaxon	LEVOBETAXOLOL	Alcon Pharms Ltd	marketed	levobetaxolol	Beta-1 adrenergic receptor	2000-01-01
Genesa	ARBUTAMINE		marketed	arbutamine	Beta-1 adrenergic receptor	1997-01-01
Zebeta	BISOPROLOL	Teva	marketed	beta-Adrenergic Blocker	Beta-1 adrenergic receptor	1992-01-01
Levadil	DILEVALOL		marketed	dilevalol	Alpha-1A adrenergic receptor, Alpha-1B adrenergic receptor, Beta-1 adrenergic receptor	1990-01-01
Optipranolol	METIPRANOLOL	Bausch Health	marketed	beta-Adrenergic Blocker	Beta-1 adrenergic receptor	1989-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Beta-1 selective adrenergic receptor antagonist (beta-blocker) class)

Ain Shams University · 1 drug in this class
Merck KGaA, Darmstadt, Germany · 1 drug in this class
Tel-Aviv Sourasky Medical Center · 1 drug in this class
University of Florida · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Metoprolol (MET) — Competitive Intelligence Brief. https://druglandscape.com/ci/metoprolol-met. Accessed 2026-05-14.

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