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Metolazone concurrently with furosemide — Competitive Intelligence Brief
marketed
Thiazide-like diuretic and loop diuretic combination
Sodium-chloride cotransporter (NCC) and sodium-potassium-chloride cotransporter (NKCC2)
Cardiovascular
Small molecule
Live · refreshed every 30 min
Target snapshot
Metolazone concurrently with furosemide (Metolazone concurrently with furosemide) — University of Maryland, Baltimore. Metolazone and furosemide together act as synergistic diuretics that block sodium reabsorption at different nephron sites to produce enhanced fluid and electrolyte excretion.
Comparator set
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Metolazone concurrently with furosemide TARGET | Metolazone concurrently with furosemide | University of Maryland, Baltimore | marketed | Thiazide-like diuretic and loop diuretic combination | Sodium-chloride cotransporter (NCC) and sodium-potassium-chloride cotransporter (NKCC2) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Thiazide-like diuretic and loop diuretic combination class)
- University of Maryland, Baltimore · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Metolazone concurrently with furosemide — Competitive Intelligence Brief. https://druglandscape.com/ci/metolazone-concurrently-with-furosemide. Accessed 2026-05-17.
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