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Metoclopramide, Granisetron, or Ondansetron — Competitive Intelligence Brief
Target snapshot
Metoclopramide, Granisetron, or Ondansetron (Metoclopramide, Granisetron, or Ondansetron) — Sanofi. This is a combination of three distinct antiemetic agents with different mechanisms: metoclopramide blocks dopamine receptors and enhances acetylcholine effects to increase gastric motility, while granisetron and ondansetron are 5-HT3 receptor antagonists that block serotonin signaling in the chemoreceptor trigger zone.
Comparator set
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Metoclopramide, Granisetron, or Ondansetron TARGET | Metoclopramide, Granisetron, or Ondansetron | Sanofi | marketed | Antiemetic agents (dopamine antagonist, 5-HT3 receptor antagonists) | Dopamine receptors (metoclopramide); 5-HT3 receptors (granisetron, ondansetron) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Antiemetic agents (dopamine antagonist, 5-HT3 receptor antagonists) class)
- Sanofi · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Metoclopramide, Granisetron, or Ondansetron — Competitive Intelligence Brief. https://druglandscape.com/ci/metoclopramide-granisetron-or-ondansetron. Accessed 2026-05-17.
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