Who are Depo-Medrol's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Durezol, Arnuity Ellipta, Omnaris, Omnaris, Mifeprex, Lotemax.

How often does this brief refresh?

Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-14 · How we verify

Depo-Medrol — Competitive Intelligence Brief

Depo-Medrol (METHYLPREDNISOLONE ACETATE) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Corticosteroid. Area: Oncology.

marketed Corticosteroid Glucocorticoid receptor Oncology Small molecule Live · refreshed every 30 min

Target snapshot

Depo-Medrol (METHYLPREDNISOLONE ACETATE) — Pfizer. Depo-Medrol works by binding to the glucocorticoid receptor, which then regulates the expression of genes involved in inflammation and immune response.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Depo-Medrol TARGET	METHYLPREDNISOLONE ACETATE	Pfizer	marketed	Corticosteroid	Glucocorticoid receptor	1959-01-01
Durezol	DIFLUPREDNATE	Novartis	marketed	difluprednate	Glucocorticoid receptor	2008-01-01
Arnuity Ellipta	FLUTICASONE FUROATE	Haleon Us Holdings	marketed	Corticosteroid	Glucocorticoid receptor	2007-01-01
Omnaris	Alvesco	Takeda Gmbh	marketed	ciclesonide	Glucocorticoid receptor	2006-01-01
Omnaris	CICLESONIDE	Covis	marketed	ciclesonide	Glucocorticoid receptor	2006-01-01
Mifeprex	MIFEPRISTONE	Corcept Therap	marketed	Progestin Antagonist [EPC]	Glucocorticoid receptor	2000-01-01
Lotemax	LOTEPREDNOL ETABONATE	Bausch Health	marketed	Corticosteroid	Glucocorticoid receptor	1998-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

2028-02-01 — Omnaris · 8371292 · US
2033-05-03 — Lotemax · 9056057 · Formulation · US
2033-05-03 — Lotemax · 9532955 · Method of Use · US
2033-05-03 — Lotemax · 10058511 · Formulation · US
2033-05-03 — Lotemax · 11219596 · Method of Use · US
2033-05-03 — Lotemax · 11219597 · Method of Use · US
2033-05-03 — Lotemax · 11596599 · Method of Use · US
2033-05-03 — Lotemax · 10857096 · Method of Use · US
2033-05-03 — Lotemax · 10864219 · Method of Use · US
2033-05-03 — Lotemax · 10945948 · Method of Use · US
2033-05-03 — Lotemax · 10940108 · Method of Use · US
2033-05-03 — Lotemax · 9737491 · Method of Use · US
2033-05-03 — Lotemax · 9827191 · Formulation · US
2033-05-03 — Lotemax · 11872318 · Formulation · US
2033-05-03 — Lotemax · 9393213 · Formulation · US
2033-05-03 — Lotemax · 10646436 · Formulation · US
2033-05-03 — Lotemax · 10993908 · Method of Use · US
2033-05-03 — Lotemax · 12115246 · Formulation · US
2033-05-03 — Lotemax · 10688045 · Formulation · US
2033-05-03 — Lotemax · 11642317 · Formulation · US
2033-05-03 — Lotemax · 10646437 · Formulation · US
2036-01-26 — Lotemax · 11534395 · Formulation · US
2036-12-23 — Lotemax · 10596107 · Formulation · US

Sponsor landscape (Corticosteroid class)

· 22 drugs in this class
Pfizer · 9 drugs in this class
Chiesi Farmaceutici S.p.A. · 6 drugs in this class
Assistance Publique - Hôpitaux de Paris · 6 drugs in this class
Merck & Co. · 5 drugs in this class
LEO Pharma · 4 drugs in this class
Allergan · 4 drugs in this class
AbbVie · 4 drugs in this class
Bristol-Myers Squibb · 3 drugs in this class
Bausch Health · 3 drugs in this class

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Cite this brief

Drug Landscape (2026). Depo-Medrol — Competitive Intelligence Brief. https://druglandscape.com/ci/methylprednisolone-acetate. Accessed 2026-05-14.

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