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Methyl Aminolaevulinate 16% Cream — Competitive Intelligence Brief
marketed
Photosensitizing agent
Protoporphyrin IX (via aminolaevulinic acid pathway)
Dermatology
Small molecule
Live · refreshed every 30 min
Target snapshot
Methyl Aminolaevulinate 16% Cream (Methyl Aminolaevulinate 16% Cream) — Galderma R&D. Methyl aminolaevulinate is a photosensitizing prodrug that accumulates in abnormal skin cells and generates reactive oxygen species when activated by red light, destroying target lesions.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Methyl Aminolaevulinate 16% Cream TARGET | Methyl Aminolaevulinate 16% Cream | Galderma R&D | marketed | Photosensitizing agent | Protoporphyrin IX (via aminolaevulinic acid pathway) | |
| verteporfin PDT | verteporfin PDT | QLT Inc. | marketed | Photosensitizing agent | Lipoprotein receptors on neovascular endothelial cells | |
| Verteporfin Photodynamic Therapy | Verteporfin Photodynamic Therapy | Novartis | marketed | Photosensitizing agent | Lipoprotein receptors on neovascular endothelial cells | |
| Levulan® Kerastick® | Levulan® Kerastick® | Medical Dermatology Specialists | marketed | Photosensitizing agent | Protoporphyrin IX (photodynamic therapy precursor) | |
| Verteporfin for injection | Verteporfin for injection | Novartis | marketed | Photosensitizing agent | Lipoprotein receptors on neovascular endothelial cells | |
| MAL | MAL | Photocure | marketed | Photosensitizing agent | Protoporphyrin IX (via aminolevulinic acid pathway) | |
| Metvix cream | Metvix cream | Galderma R&D | phase 3 | Photosensitizing agent | Protoporphyrin IX (via aminolevulinic acid pathway) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Photosensitizing agent class)
- Galderma R&D · 4 drugs in this class
- Novartis · 2 drugs in this class
- QLT Inc. · 2 drugs in this class
- Medical Dermatology Specialists · 1 drug in this class
- Photocure · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Methyl Aminolaevulinate 16% Cream — Competitive Intelligence Brief. https://druglandscape.com/ci/methyl-aminolaevulinate-16-cream. Accessed 2026-05-17.
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