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Methadone; NAC — Competitive Intelligence Brief
marketed
Opioid agonist with antioxidant adjunct
Mu opioid receptor (methadone); glutathione synthesis pathway (NAC)
Pain Management, Substance Use Disorder
Small molecule
Live · refreshed every 30 min
Target snapshot
Methadone; NAC (Methadone; NAC) — Taichung Veterans General Hospital. Methadone is a synthetic opioid agonist that binds to mu opioid receptors in the central nervous system, while NAC (N-acetylcysteine) is an antioxidant that replenishes glutathione and may modulate opioid-related neurotoxicity.
Comparator set
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Methadone; NAC TARGET | Methadone; NAC | Taichung Veterans General Hospital | marketed | Opioid agonist with antioxidant adjunct | Mu opioid receptor (methadone); glutathione synthesis pathway (NAC) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Opioid agonist with antioxidant adjunct class)
- Taichung Veterans General Hospital · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Methadone; NAC — Competitive Intelligence Brief. https://druglandscape.com/ci/methadone-nac. Accessed 2026-05-13.
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