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Methadone Hydrochloride — Competitive Intelligence Brief

Methadone Hydrochloride (METHADONE) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Opioid Agonist. Area: Neuroscience.

marketed Opioid Agonist mu-opioid receptors, NMDA receptor Neuroscience Small molecule Live · refreshed every 30 min

Target snapshot

Methadone Hydrochloride (METHADONE) — Specgx Llc. Methadone is a synthetic opioid that acts as a mu-agonist, providing analgesia and aiding in opioid addiction management.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Methadone Hydrochloride TARGET METHADONE Specgx Llc marketed Opioid Agonist mu-opioid receptors, NMDA receptor 1947-01-01
BENZHYDROCODONE BENZHYDROCODONE marketed Opioid analgesic combination; full mu-opioid agonist with non-opioid analgesic Mu-opioid receptors (primary); delta and kappa opioid receptors (secondary); central nervous system pain pathways 2018-01-01
Nucynta TAPENTADOL Collegium Pharm Inc marketed Opioid Agonist Mu-type opioid receptor 2008-01-01
Alfenta ALFENTANIL Rising marketed Opioid Agonist Mu-type opioid receptor 1986-01-01
Dilaudid-Hp HYDROMORPHONE Fresenius Kabi marketed Opioid Agonist mu-opioid receptor 1984-01-01
Sufenta Preservative Free SUFENTANIL Rising marketed Opioid Agonist Mu-type opioid receptor 1984-01-01
Dilaudid-Hp Hydromorphone Hydrochloride Fresenius Kabi marketed Opioid agonist Mu-opioid receptor 1984-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Opioid Agonist class)

  1. · 4 drugs in this class
  2. Rising · 2 drugs in this class
  3. Pfizer · 2 drugs in this class
  4. Endo · 1 drug in this class
  5. Fresenius Kabi · 1 drug in this class
  6. Specgx Llc · 1 drug in this class
  7. Teva · 1 drug in this class
  8. Bausch Health · 1 drug in this class
  9. Collegium Pharm Inc · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Methadone Hydrochloride — Competitive Intelligence Brief. https://druglandscape.com/ci/methadone. Accessed 2026-05-13.

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