Who are metformin + glimepiride's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): MET + Glibenclamide Group, metformin+ gliclazide.

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Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-14 · How we verify

metformin + glimepiride — Competitive Intelligence Brief

metformin + glimepiride (metformin + glimepiride) competitive landscape: 2 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Antidiabetic combination (biguanide + sulfonylurea). Area: Diabetes.

marketed Antidiabetic combination (biguanide + sulfonylurea) Metformin: mitochondrial glycerophosphate dehydrogenase; Glimepiride: ATP-sensitive potassium channel (KATP) Diabetes Small molecule Live · refreshed every 30 min

Target snapshot

metformin + glimepiride (metformin + glimepiride) — GlaxoSmithKline. This combination reduces blood glucose by increasing insulin secretion and improving insulin sensitivity in type 2 diabetes patients.

Comparator set (2 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
metformin + glimepiride TARGET	metformin + glimepiride	GlaxoSmithKline	marketed	Antidiabetic combination (biguanide + sulfonylurea)	Metformin: mitochondrial glycerophosphate dehydrogenase; Glimepiride: ATP-sensitive potassium channel (KATP)
MET + Glibenclamide Group	MET + Glibenclamide Group	Hospital de Clinicas de Porto Alegre	marketed	Antidiabetic combination (biguanide + sulfonylurea)	AMPK pathway (metformin); ATP-sensitive potassium channel (glibenclamide)
metformin+ gliclazide	metformin+ gliclazide	GlaxoSmithKline	marketed	Antidiabetic combination (biguanide + sulfonylurea)	Metformin: mitochondrial glycerophosphate dehydrogenase; Gliclazide: ATP-sensitive potassium channels on pancreatic beta cells

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Antidiabetic combination (biguanide + sulfonylurea) class)

GlaxoSmithKline · 2 drugs in this class
Hospital de Clinicas de Porto Alegre · 1 drug in this class

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Cite this brief

Drug Landscape (2026). metformin + glimepiride — Competitive Intelligence Brief. https://druglandscape.com/ci/metformin-glimepiride. Accessed 2026-05-14.

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