Last reviewed · How we verify
Megestrol Acetate and olanzapine — Competitive Intelligence Brief
phase 3
Progestin + atypical antipsychotic combination
Hypothalamic appetite centers (megestrol); dopamine D2 and serotonin 5-HT2A receptors (olanzapine)
Oncology / Palliative Care / Cachexia
Small molecule
Live · refreshed every 30 min
Target snapshot
Megestrol Acetate and olanzapine (Megestrol Acetate and olanzapine) — Qingdao Central Hospital. This combination uses megestrol acetate (a progestin) to stimulate appetite and promote weight gain, while olanzapine (an atypical antipsychotic) provides additional appetite stimulation and may address underlying psychiatric or behavioral symptoms.
Comparator set
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Megestrol Acetate and olanzapine TARGET | Megestrol Acetate and olanzapine | Qingdao Central Hospital | phase 3 | Progestin + atypical antipsychotic combination | Hypothalamic appetite centers (megestrol); dopamine D2 and serotonin 5-HT2A receptors (olanzapine) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Progestin + atypical antipsychotic combination class)
- Qingdao Central Hospital · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Megestrol Acetate and olanzapine — Competitive Intelligence Brief. https://druglandscape.com/ci/megestrol-acetate-and-olanzapine. Accessed 2026-05-16.
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