Who are MEDI4736 + Tremelimumab's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Durvalumab +Tremelimumab.

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Last reviewed 2026-05-17 · How we verify

MEDI4736 + Tremelimumab — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

MEDI4736 + Tremelimumab (MEDI4736 + Tremelimumab) competitive landscape: 1 comparator, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Dual checkpoint inhibitor (PD-L1 inhibitor + CTLA-4 inhibitor). Area: Oncology.

phase 3 Dual checkpoint inhibitor (PD-L1 inhibitor + CTLA-4 inhibitor) PD-L1 and CTLA-4 Oncology Small molecule Live · refreshed every 30 min

Target snapshot

MEDI4736 + Tremelimumab (MEDI4736 + Tremelimumab) — AstraZeneca. MEDI4736 (durvalumab) blocks PD-L1 to restore anti-tumor immunity, while tremelimumab blocks CTLA-4 to enhance T-cell activation, together providing dual checkpoint inhibition.

Comparator set (1 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
MEDI4736 + Tremelimumab TARGET	MEDI4736 + Tremelimumab	AstraZeneca	phase 3	Dual checkpoint inhibitor (PD-L1 inhibitor + CTLA-4 inhibitor)	PD-L1 and CTLA-4
Durvalumab +Tremelimumab	Durvalumab +Tremelimumab	AstraZeneca	phase 3	Dual checkpoint inhibitor combination (PD-L1 inhibitor + CTLA-4 inhibitor)	PD-L1 and CTLA-4

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Dual checkpoint inhibitor (PD-L1 inhibitor + CTLA-4 inhibitor) class)

AstraZeneca · 1 drug in this class

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Cite this brief

Drug Landscape (2026). MEDI4736 + Tremelimumab — Competitive Intelligence Brief. https://druglandscape.com/ci/medi4736-tremelimumab. Accessed 2026-05-17.

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