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MEDI3250 — Competitive Intelligence Brief

MEDI3250 (MEDI3250) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Bispecific antibody; PD-L1/4-1BB bispecific. Area: Oncology.

phase 3 Bispecific antibody; PD-L1/4-1BB bispecific PD-L1 and 4-1BB (CD137) Oncology Small molecule Live · refreshed every 30 min

Target snapshot

MEDI3250 (MEDI3250) — AstraZeneca. MEDI3250 is a bispecific antibody that simultaneously engages PD-L1 on tumor cells and 4-1BB on T cells to enhance anti-tumor immune responses.

Comparator set (6 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
MEDI3250 TARGET MEDI3250 AstraZeneca phase 3 Bispecific antibody; PD-L1/4-1BB bispecific PD-L1 and 4-1BB (CD137)
Elrexfio Elranatamab Pfizer marketed Bispecific antibody BCMA (B-cell maturation antigen) on plasma cells, plasmablasts, and multiple myeloma cells; CD3 on T-cells 2023-01-01
Elrexfio elranatamab Pfizer marketed Bispecific antibody BCMA (B-cell maturation antigen) on plasma cells, plasmablasts, and multiple myeloma cells; CD3 on T-cells 2023-01-01
Elrantamab elrantamab Pfizer marketed Bispecific Antibody BCMA (B-cell maturation antigen)
HZT-501 HZT-501 Amgen phase 3 Bispecific antibody
BAT1706 BAT1706 Bio-Thera Solutions phase 3 Bispecific antibody; PD-1/TGF-β inhibitor PD-1 and TGF-β
BAT2206 BAT2206 Bio-Thera Solutions phase 3 Bispecific antibody; dual checkpoint inhibitor Likely PD-1 and LAG-3 (or similar dual checkpoint targets)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Bispecific antibody; PD-L1/4-1BB bispecific class)

  1. AstraZeneca · 1 drug in this class

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Cite this brief

Drug Landscape (2026). MEDI3250 — Competitive Intelligence Brief. https://druglandscape.com/ci/medi3250. Accessed 2026-05-13.

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