Who are MCI-186's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Radicava ORS, Edaravone Dexborneol, N-Acetylcysteine Amide, NXY-059, Compound Edaravone Injection, MCI-186 in open label phase.

How often does this brief refresh?

Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-14 · How we verify

MCI-186 — Competitive Intelligence Brief

MCI-186 (MCI-186) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Free radical scavenger; antioxidant. Area: Neurology.

phase 3 Free radical scavenger; antioxidant Reactive oxygen species (ROS); hydroxyl radicals; peroxynitrite Neurology Small molecule Live · refreshed every 30 min

Target snapshot

MCI-186 (MCI-186) — Tanabe Pharma Corporation. MCI-186 is a free radical scavenger that neutralizes reactive oxygen species and reduces oxidative stress in neuronal tissue.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
MCI-186 TARGET	MCI-186	Tanabe Pharma Corporation	phase 3	Free radical scavenger; antioxidant	Reactive oxygen species (ROS); hydroxyl radicals; peroxynitrite
Radicava ORS	Radicava ORS	Shanghai Auzone Biological Technology Co., Ltd.	marketed	Free radical scavenger; antioxidant	Free radicals (hydroxyl radicals); non-selective antioxidant mechanism
Edaravone Dexborneol	Edaravone Dexborneol	First Affiliated Hospital, Sun Yat-Sen University	marketed	Free radical scavenger combination
N-Acetylcysteine Amide	N-Acetylcysteine Amide	Nacuity Pharmaceuticals, Inc.	phase 3	Antioxidant / Free radical scavenger	Intracellular glutathione synthesis; free radicals / reactive oxygen species
NXY-059	NXY-059	AstraZeneca	phase 3	Free radical scavenger / Neuroprotective agent	Reactive oxygen species (ROS) / Free radicals
Compound Edaravone Injection	Compound Edaravone Injection	Jiangsu Simcere Pharmaceutical Co., Ltd.	phase 3	Free radical scavenger / Antioxidant	Hydroxyl radicals and reactive oxygen species
MCI-186 in open label phase	MCI-186 in open label phase	Tanabe Pharma Corporation	phase 3	Free radical scavenger

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Free radical scavenger; antioxidant class)

Shanghai Auzone Biological Technology Co., Ltd. · 1 drug in this class
Tanabe Pharma Corporation · 1 drug in this class

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Cite this brief

Drug Landscape (2026). MCI-186 — Competitive Intelligence Brief. https://druglandscape.com/ci/mci-186. Accessed 2026-05-14.

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