Bupivacaine Hydrochloride And Epinephrine — Competitive Intelligence Brief

Bupivacaine Hydrochloride And Epinephrine (Bupivacaine Hydrochloride) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Local anesthetic.

marketed Local anesthetic Sodium channels Small molecule

Target snapshot

Bupivacaine Hydrochloride And Epinephrine (Bupivacaine Hydrochloride) — Pfizer. Bupivacaine blocks nerve impulses by increasing the threshold for electrical excitation, slowing nerve impulse propagation, and reducing the rate of rise of the action potential.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Bupivacaine Hydrochloride And Epinephrine TARGET	Bupivacaine Hydrochloride	Pfizer	marketed	Local anesthetic	Sodium channels	1972-01-01
Cordarone	AMIODARONE	Pfizer	marketed	Antiarrhythmic	sodium channels, potassium channels, calcium channels	1985-01-01
MEXILETINE HYDROCHLORIDE	MEXILETINE HYDROCHLORIDE		marketed		sodium channels	1985-01-01
Norpace Cr	Disopyramide Phosphate	Pfizer	marketed	Type 1 antiarrhythmic	Cardiac sodium channels; cardiac cells with augmented automaticity	1977-01-01
Bupivacaine Hydrochloride And Epinephrine	Bupivacaine Hydrochloride	Pfizer	marketed	Amide local anesthetic	Nerve sodium channels	1972-01-01
Bupivacaine Hydrochloride And Epinephrine	Bupivacaine Hydrochloride	Pfizer	marketed	Amide local anesthetic	Nerve sodium channels	1972-01-01
Bupivacaine Hydrochloride	Bupivacaine Hydrochloride	Pfizer	marketed	Amide-type local anesthetic	Nerve sodium channels	1972-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

• 2029-05-20 — Bupivacaine Hydrochloride · RE47826 · US
• 2034-03-13 — Bupivacaine Hydrochloride · 10398686 · US
• 2034-03-13 — Bupivacaine Hydrochloride · 11253504 · US
• 2034-03-13 — Bupivacaine Hydrochloride · 9592227 · US
• 2034-03-13 — Bupivacaine Hydrochloride · 9744163 · US
• 2034-03-13 — Bupivacaine Hydrochloride · 9913909 · US
• 2035-04-20 — Bupivacaine Hydrochloride · 9694079 · US
• 2035-04-20 — Bupivacaine Hydrochloride · 9801945 · US
• 2035-04-20 — Bupivacaine Hydrochloride · 10098957 · US
• 2035-04-20 — Bupivacaine Hydrochloride · 10213510 · US
• 2035-04-20 — Bupivacaine Hydrochloride · 10632199 · US
• 2035-04-20 — Bupivacaine Hydrochloride · 10898575 · US
• 2035-04-20 — Bupivacaine Hydrochloride · 10980886 · US
• 2035-04-20 — Bupivacaine Hydrochloride · 11083730 · US
• 2035-04-20 — Bupivacaine Hydrochloride · 11083797 · US
• 2035-04-20 — Bupivacaine Hydrochloride · 11413350 · US
• 2041-01-12 — Bupivacaine Hydrochloride · 11400019 · US
• 2041-01-22 — Bupivacaine Hydrochloride · 11452691 · US
• 2041-01-22 — Bupivacaine Hydrochloride · 11179336 · US
• 2041-01-22 — Bupivacaine Hydrochloride · 11278494 · US
• 2041-01-22 — Bupivacaine Hydrochloride · 11304904 · US
• 2041-01-22 — Bupivacaine Hydrochloride · 11311486 · US
• 2041-01-22 — Bupivacaine Hydrochloride · 11357727 · US
• 2041-01-22 — Bupivacaine Hydrochloride · 11426348 · US
• 2041-01-22 — Bupivacaine Hydrochloride · 11033495 · US

Sponsor landscape (Local anesthetic class)

1. University of California, San Diego · 3 drugs in this class
2. Durect · 3 drugs in this class
3. Pacira Pharmaceuticals, Inc · 3 drugs in this class
4. Wake Forest University Health Sciences · 3 drugs in this class
5. Medical University of Vienna · 3 drugs in this class
6. Imperial College London · 2 drugs in this class
7. Hvidovre University Hospital · 2 drugs in this class
8. Innocoll · 2 drugs in this class
9. George Washington University · 2 drugs in this class
10. Guy's and St Thomas' NHS Foundation Trust · 2 drugs in this class