Who are Bupivacaine Hydrochloride And Epinephrine's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Chirocain, Mentax, PERHEXILINE, Bupivacaine Hydrochloride And Epinephrine, DIPHENIDOL HYDROCHLORIDE, Dopram.

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Last reviewed 2026-05-17 · How we verify

Bupivacaine Hydrochloride And Epinephrine — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Bupivacaine Hydrochloride And Epinephrine (Bupivacaine Hydrochloride) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Amide Local Anesthetic.

marketed Amide Local Anesthetic Cytochrome P450 2D6 Small molecule Live · refreshed every 30 min

Target snapshot

Bupivacaine Hydrochloride And Epinephrine (Bupivacaine Hydrochloride) — Pfizer. Bupivacaine Hydrochloride blocks nerve impulses by inhibiting sodium channels.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Bupivacaine Hydrochloride And Epinephrine TARGET	Bupivacaine Hydrochloride	Pfizer	marketed	Amide Local Anesthetic	Cytochrome P450 2D6	1972-01-01
Chirocain	LEVOBUPIVACAINE	Purdue Pharma Lp	marketed	levobupivacaine	Cytochrome P450 2D6	1999-01-01
Mentax	BUTENAFINE	Bayer	marketed	Benzylamine Antifungal	Cytochrome P450 2D6	1996-01-01
PERHEXILINE	PERHEXILINE		marketed	perhexiline	Carnitine O-palmitoyltransferase 1, liver isoform, Carnitine O-palmitoyltransferase 2, mitochondrial, Cytochrome P450 2D6	1974-01-01
Bupivacaine Hydrochloride And Epinephrine	BUPIVACAINE	Innocoll	marketed	Amide Local Anesthetic	Cytochrome P450 2D6	1972-01-01
DIPHENIDOL HYDROCHLORIDE	DIPHENIDOL HYDROCHLORIDE		marketed	Anticholinergic	5-hydroxytryptamine receptor 2A, Cytochrome P450 2D6, D(2) dopamine receptor	1967-01-01
Dopram	DOXAPRAM	Hikma	marketed	Respiratory Stimulant	Cytochrome P450 2D6	1965-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Amide Local Anesthetic class)

· 1 drug in this class
Eastman Kodak · 1 drug in this class
Fresenius Kabi · 1 drug in this class
Innocoll · 1 drug in this class
Pfizer · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Bupivacaine Hydrochloride And Epinephrine — Competitive Intelligence Brief. https://druglandscape.com/ci/marcaine-hydrochloride-preservative-free. Accessed 2026-05-17.

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